SynthesisFrontiers in endocrinology2021
Impact of Diabetes Mellitus on Lower Urinary Tract Symptoms in Benign Prostatic Hyperplasia Patients: A Meta-Analysis.
Synthesis in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- The gut-prostate axis in benign prostatic diseases: Mechanistic pathways and therapeutic implications.iScience · 2026Review
- Exercise and Physical Activity as Modifiable Risk Factors for Benign Prostatic Hyperplasia: An Update.Current urology reports · 2026Review
- Evidence for the Additional Health Benefits Associated with Phosphodiesterase 5 Inhibitors when Used for Treating Erectile Dysfunction, with a Focus on Prostate Cancer Patients and Other Associated Conditions.The world journal of men's health · 2026Review
- Fatty liver and diabetes are related to benign prostate hyperplasia.Hormones (Athens, Greece) · 2026Article
- Rates and Predictors of Persistent LUTS Medication Use After Laser Enucleation of the Prostate.Lower urinary tract symptoms · 2026Article
- Lower urinary tract dysfunction in the diabetes population: endocrinologists knowledge base and clinical practice patterns.Irish journal of medical science · 2026Article
- Observational
- Incidence and predictors of transurethral resection of prostate in men with and without type 2 diabetes: the Fremantle Diabetes Study Phase I.Internal medicine journal · 2025Article
- Cross-sectional study on the association between serum uric acid levels and the risk of benign prostatic hyperplasia.BMJ open · 2025Article
- Risk of poor glycemic control in tamsulosin versus finasteride users with type 2 diabetes mellitus.Heliyon · 2025Article
- Astragaloside IV Improves Cognitive Impairment by Reducing β-Amyloid and Tau Protein Deposition in Hippocampal Tissue of db/db Mice: A PET/CT Imaging-Based Study.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025Article
- Prostate Dimensions and Their Impact on LUTS and Erectile Function: Is Length the Missing Link?Journal of clinical medicine · 2024Article
- Exploring the association between caffeine intake and benign prostatic hyperplasia: results from the NHANES 2005-2008.Frontiers in nutrition · 2024Article
- High glucose promotes benign prostatic hyperplasia by downregulating PDK4 expression.Scientific reports · 2023Article
- Voiding function improves under long-term testosterone treatment (TTh) in hypogonadal men, independent of prostate size.International urology and nephrology · 2023Article
- A Scientometric Visualization Analysis for Benign Prostatic Hyperplasia from 2016 to 2022.Urologia internationalis · 2023Review
- An evaluation of lower urinary tract symptoms in diabetic patients: a cross-sectional study.BMC urology · 2022Article
Corrections and comments
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Authors and funding
6 authors.
Funding
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Abstract
Background: Benign prostatic hyperplasia (BPH) is a disease that causes lower urinary tract symptoms (LUTS), which are the most common urological problem in approximately one-third of the male population aged over 50 years. Some studies have suggested that diabetes may be a risk factor for the development of BPH. However, whether diabetes aggravates the LUTS of BPH patients is still controversial. Aim: To investigate the impact of diabetes mellitus on LUTS in BPH patients. Methods: A literature search was conducted using Web of Science, Embase, PubMed, and China National Knowledge Infrastructure literature databases. This meta-analysis was registered in PROSPERO (registration number: CRD 42020200794). Fixed- or random-effects models were used for analysis according to heterogeneity. The results of the systematic analysis are presented as weighted mean difference (WMD) with the corresponding 95% confidence intervals (CI). Results: In total, 1308 studies were retrieved from databases and 18 articles comprising 1685 cases and 4653 controls were selected for meta-analysis. The results of the meta-analysis showed that the International Prostate Symptom Score (IPSS) value and prostate volume of BPH patients with diabetes was significantly higher than that of BPH patients without diabetes. Conclusions: This systematic review is the first to evaluate the impact of diabetes mellitus on LUTS in BPH patients. The results of our meta-analysis support the hypothesis that LUTS in BPH patients is increased in patients with diabetes mellitus compared with controls, which suggests that physicians should pay more attention to BPH patients with diabetes mellitus. Systematic Review Registration: PROSPERO [https://www.crd.york.ac.uk/PROSPERO/display_record.php?RecordID=200794], identifier CRD 42020200794.
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