Evidence map›Paper›PMID 35178022›Full record

ArticleFrontiers in neurology2021

Myoclonic Epilepsy: Case Report of a Mild Phenotype in a Pediatric Patient Expanding Clinical Spectrum of

Lorenzo Perilli, Gioia Mastromoro, Manuel Murciano, Ilaria Amedeo, Federica Avenoso, Antonio Pizzuti, Cristiana Alessia Guido, Alberto Spalice

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Lorenzo PerilliDepartment of Mother and Child and Urological Sciences, Sapienza University of Rome, Rome, Italy.
Gioia MastromoroFaculty of Medicine and Dentistry, Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy.
Manuel MurcianoDepartment of Mother and Child and Urological Sciences, Sapienza University of Rome, Rome, Italy.
Ilaria AmedeoDepartment of Mother and Child and Urological Sciences, Sapienza University of Rome, Rome, Italy.
Federica AvenosoDepartment of Mother and Child and Urological Sciences, Sapienza University of Rome, Rome, Italy.
Antonio PizzutiFaculty of Medicine and Dentistry, Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy.
Cristiana Alessia GuidoDepartment of Mother and Child and Urological Sciences, Sapienza University of Rome, Rome, Italy.
Alberto SpaliceDepartment of Mother and Child and Urological Sciences, Sapienza University of Rome, Rome, Italy.
Sapienza University of Rome · ITBambino Gesù Children's Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report on the rare case of a male toddler presenting with myoclonic epilepsy characterized by daily episodes of upward movements of the eyebrows, and myoclonic jerks of both head and upper limbs. In addition, the child showed speech delay, tremors, and lack of motor coordination. Next Generation Sequencing analysis (NGS) performed in trio revealed in the proband the c.889C>T

Indexed as

classificationdrug therapyepilepsyepilepsy—abnormalitiesepileptic encephalopathiesgenetic variantsgenotype-first approachKCNA2

Identifiers

PMID35178022
PMCPMC8844549
OpenAlexW4210700017

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.