Evidence map›Paper›PMID 35177914›Full record

ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2022

The Anti-Obesity Potential of

Muhammed Majeed, Kalyanam Nagabhushanam, Beena Bhat, Mohammad Ansari, Anjali Pandey, Sarang Bani, Lakshmi Mundkur

Open access · goldAbstract read
In one paragraph

Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Muhammed MajeedResearch and Development, Sami-Sabinsa Group Limited, Bangalore, India.ORCID 0000-0002-1690-7470
Kalyanam NagabhushanamResearch and Development, Natural Product Chemistry Sabinsa Corporation, East Windsor, NJ, USA.ORCID 0000-0001-9470-4110
Beena BhatResearch and Development, Phytochemistry, Sami-Sabinsa Group Limited, Bangalore, India.
Mohammad AnsariResearch and Development, Phytochemistry, Sami-Sabinsa Group Limited, Bangalore, India.
Anjali PandeyResearch and Development, Biological Research, Sami-Sabinsa Group Limited, Bangalore, India.
Sarang BaniResearch and Development, Biological Research, Sami-Sabinsa Group Limited, Bangalore, India.
Lakshmi MundkurResearch and Development, Biological Research, Sami-Sabinsa Group Limited, Bangalore, India.ORCID 0000-0003-2928-1726
Sami Labs (India) · INWindsor Dermatology · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeObesity is a complex medical problem that increases the risk of other diseases like diabetes, cardiovascular diseases, and fatty liver disease. The present study evaluated the efficacy and safety of MATERIALS AND

methodsThe efficacy, safety, and tolerability of CRE were evaluated in 30 obese individuals with a BMI of 30 to 40 kg/m

resultsThe pilot clinical study showed a reduction in body weight with a significant decrease in waist circumference and BMI. The serum lipid profile showed a significant improvement in CRE-treated individuals. The extract was well tolerated, and no adverse effects were reported at the end of the study. CRE showed a dose-dependent adipogenesis reduction in vitro with an IC

conclusionCRE has anti-adipogenic properties, is safe for human consumption, and effectively manages weight and hypercholesterolemia in overweight individuals.

Indexed as

adipogenesisCyperus rotundusleptinlipid levelsobesitypiceatannolrandomized clinical trialScirpusin AScirpusin B

Identifiers

PMID35177914
PMCPMC8843772
OpenAlexW4210907344

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.