ReviewNPJ digital medicine2022
Health-focused conversational agents in person-centered care: a review of apps.
Review in NPJ digital medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
45 citing papers in PubMed, 3 syntheses or guidelines pooled it, 111 citations in OpenAlex.
- Initial Requirements for the Prototyping of an App for a Psychosocial Rehabilitation Project: An Integrative Review.International journal of environmental research and public health · 2025Pooled it
- Conversational AI and Vaccine Communication: Systematic Review of the Evidence.Journal of medical Internet research · 2023Pooled it
- Pooled it
- A behaviourally informed chatbot increases vaccination rates in Argentina more than a one-way reminder.Nature human behaviour · 2024Trial
- Using a Chatbot as an Alternative Approach for In-Person Toothbrushing Training During the COVID-19 Pandemic: Comparative Study.Journal of medical Internet research · 2022Trial
- Real-world use and evaluation of a generative AI chatbot for Parkinson's disease information: a prospective observational study.The Lancet regional health. Europe · 2026Article
- Coconstructing CHAMP, an Artificial Intelligence Chatbot for Pediatric Infectious Symptoms Management: Protocol for a Multiphase Participatory Study.JMIR research protocols · 2026Article
- Technology-mediated screening interviews for youth mental health: Content validation, randomized controlled trial, and expert evaluation.PLOS digital health · 2026Article
- AI-Enhanced Conversational Agents for Personalized Asthma Support in People With Asthma: Factors for Engagement, Value, and Efficacy in a Cross-Sectional Survey Study.JMIR human factors · 2026Article
- Article
- Perspective on patient and non-academic partner engagement for the responsible integration of large language models in health chatbots.Research involvement and engagement · 2025Article
- A systematic review of unmet needs of older adults in home settings and their implications for novel technological solutions.Innovation in aging · 2025Article
- Recommendations for Mental Health Chatbot Conversations: An Integrative Review.Journal of advanced nursing · 2025Review
- Charting the evolution of artificial intelligence mental health chatbots from rule-based systems to large language models: a systematic review.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2025Article
- Development and evaluation of a lightweight large language model chatbot for medication enquiry.PLOS digital health · 2025Article
- User Engagement with A Multimodal Conversational Agent for Self-Care and Chronic Disease Management: A Retrospective Analysis.Journal of medical systems · 2025Article
- Controversy in Hypertension: Pro-Side of the Argument Using Artificial Intelligence for Hypertension Diagnosis and Management.Hypertension (Dallas, Tex. : 1979) · 2025Review
- The evolving field of digital mental health: current evidence and implementation issues for smartphone apps, generative artificial intelligence, and virtual reality.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2025Article
- Using Large Language Models to Enhance Exercise Recommendations and Physical Activity in Clinical and Healthy Populations: Scoping Review.JMIR medical informatics · 2025Article
- Transforming Hypertension Diagnosis and Management in The Era of Artificial Intelligence: A 2023 National Heart, Lung, and Blood Institute (NHLBI) Workshop Report.Hypertension (Dallas, Tex. : 1979) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Health-focused apps with chatbots ("healthbots") have a critical role in addressing gaps in quality healthcare. There is limited evidence on how such healthbots are developed and applied in practice. Our review of healthbots aims to classify types of healthbots, contexts of use, and their natural language processing capabilities. Eligible apps were those that were health-related, had an embedded text-based conversational agent, available in English, and were available for free download through the Google Play or Apple iOS store. Apps were identified using 42Matters software, a mobile app search engine. Apps were assessed using an evaluation framework addressing chatbot characteristics and natural language processing features. The review suggests uptake across 33 low- and high-income countries. Most healthbots are patient-facing, available on a mobile interface and provide a range of functions including health education and counselling support, assessment of symptoms, and assistance with tasks such as scheduling. Most of the 78 apps reviewed focus on primary care and mental health, only 6 (7.59%) had a theoretical underpinning, and 10 (12.35%) complied with health information privacy regulations. Our assessment indicated that only a few apps use machine learning and natural language processing approaches, despite such marketing claims. Most apps allowed for a finite-state input, where the dialogue is led by the system and follows a predetermined algorithm. Healthbots are potentially transformative in centering care around the user; however, they are in a nascent state of development and require further research on development, automation and adoption for a population-level health impact.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.