Evidence map›Paper›PMID 35177760›Full record

ArticleScientific reports2022

Fine-mapping of intracranial aneurysm susceptibility based on a genome-wide association study.

Eun Pyo Hong, Dong Hyuk Youn, Bong Jun Kim, Jun Hyong Ahn, Jeong Jin Park, Jong Kook Rhim, Heung Cheol Kim, Gyojun Hwang, Hong Jun Jeon, Jin Pyeong Jeon

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Eun Pyo HongInstitute of New Frontier Research, Hallym University College of Medicine, Chuncheon, Republic of Korea.
Dong Hyuk YounInstitute of New Frontier Research, Hallym University College of Medicine, Chuncheon, Republic of Korea.
Bong Jun KimInstitute of New Frontier Research, Hallym University College of Medicine, Chuncheon, Republic of Korea.
Jun Hyong AhnDepartment of Neurosurgery, Gangwon National University College of Medicine, Chuncheon, Gangwon-do, Republic of Korea.
Jeong Jin ParkDepartment of Neurology, Konkuk University Medical Center, Seoul, Republic of Korea.
Jong Kook RhimDepartment of Neurosurgery, Jeju National University College of Medicine, Jeju, Republic of Korea.
Heung Cheol KimDepartment of Radiology, Hallym University College of Medicine, Chuncheon, Gangwon-do, Republic of Korea.
Gyojun HwangDepartment of Neurosurgery, DMC Bundang Jesaeng Hospital, Seongnam, Gyeonggi-do, Republic of Korea.
Hong Jun JeonDepartment of Neurosurgery, Hallym University College of Medicine, 77 Sakju-ro, Chuncheon, Gangwon-do, 24253, Republic of Korea.
Jin Pyeong JeonDepartment of Neurosurgery, Hallym University College of Medicine, 77 Sakju-ro, Chuncheon, Gangwon-do, 24253, Republic of Korea. jjs6553@daum.net.
Hallym University · KRBundang Jesaeng Hospital · KRJeju National University · KRKangwon National University · KRKonkuk University Medical Center · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In addition to conventional genome-wide association studies (GWAS), a fine-mapping analysis is increasingly used to identify the genetic function of variants associated with disease susceptibilities. Here, we used a fine-mapping approach to evaluate candidate variants based on a previous GWAS involving patients with intracranial aneurysm (IA). A fine-mapping analysis was conducted based on the chromosomal data provided by a GWAS of 250 patients diagnosed with IA and 296 controls using posterior inclusion probability (PIP) and log10 transformed Bayes factor (log10BF). The narrow sense of heritability (h

Indexed as

Bayes TheoremGene Expression RegulationGenetic Predisposition to DiseaseGenome-Wide Association StudyHumansIntracranial AneurysmPolymorphism, Single NucleotideProtein Interaction Maps

Identifiers

PMID35177760
PMCPMC8854430
OpenAlexW4220911527

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.