ArticleScientific reports2022
Standardised bioassays reveal that mosquitoes learn to avoid compounds used in chemical vector control after a single sub-lethal exposure.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Repellent effects of insecticides against Aedes aegypti: a systematic review.Parasites & vectors · 2025Pooled it
- Inferring the epidemiological benefit of indoor vector control interventions against malaria from mosquito data.Nature communications · 2022Pooled it
- Commercial permethrin elicits chemoreceptive responses on different Anopheles gambiae sensory appendages.Pest management science · 2026Article
- Ascending nociceptive pathways drive rapid escape and sustained avoidance in adultbioRxiv : the preprint server for biology · 2025Article
- The epidemiological benefit of pyrethroid-pyrrole insecticide treated nets against malaria: an individual-based malaria transmission dynamics modelling study.The Lancet. Global health · 2024Article
- Comparative transcriptional analysis between susceptible and resistant populations of Aedes (Stegomyia) aegypti (Linnaeus, 1762) after malathion exposure.Molecular genetics and genomics : MGG · 2024Article
- Internal and external drivers interact to create highly dynamic mosquito blood-feeding behaviour.Proceedings. Biological sciences · 2024Review
- Review
- Non-contact detection of pyrethroids widely used in vector control by Anopheles mosquitoes.PloS one · 2024Article
- A critical review of current laboratory methods used to evaluate mosquito repellents.Frontiers in insect science · 2024Review
- A bioassay method validation framework for laboratory and semi-field tests used to evaluate vector control tools.Malaria journal · 2023Article
- Transfluthrin and Metofluthrin as Effective Repellents against Pyrethroid-Susceptible and Pyrethroid-ResistantInsects · 2023Article
- WHO cone bioassay boards with or without holes: relevance for bioassay outcomes in long-lasting insecticidal net studies.Malaria journal · 2022Article
- Article
- Enhancing the Quality of Spray Application in IRS: Evaluation of the Micron Track Sprayer.Insects · 2022Article
- The ability ofWellcome open research · 2022Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vector-borne diseases are worldwide public health issues. Despite research focused on vectorial capacity determinants in pathogen transmitting mosquitoes, their behavioural plasticity remains poorly understood. Memory and associative learning have been linked to behavioural changes in several insect species, but their relevance in behavioural responses to pesticide vector control has been largely overlooked. In this study, female Aedes aegypti and Culex quinquefasciastus were exposed to sub-lethal doses of 5 pesticide compounds using modified World Health Organization (WHO) tube bioassays. Conditioned females, subsequently exposed to the same pesticides in WHO tunnel assays, exhibited behavioural avoidance by forgoing blood-feeding to ensure survival. Standardized resting site choice tests showed that pre-exposed females avoided the pesticides smell and choose to rest in a pesticide-free compartment. These results showed that, following a single exposure, mosquitoes can associate the olfactory stimulus of pesticides with their detrimental effects and subsequently avoid pesticide contact. Findings highlight the importance of mosquito cognition as determinants of pesticide resistance in mosquito populations targeted by chemical control.
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