ArticleNature communications2022
In-situ transfer vat photopolymerization for transparent microfluidic device fabrication.
Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed.
- An open-source slicer for 3D mSLA printing of microfluidic chips.Scientific reports · 2025Article
- The Principle and Development of Optical Maskless Lithography Based Digital Micromirror Device (DMD).Micromachines · 2025Review
- Pressurized photobonding for 3D-printed inertial and droplet microfluidics.Lab on a chip · 2025Article
- Advancements and Future Perspectives of Microfluidic Technology in Pediatric Healthcare.Smart medicine · 2025Review
- One-Pot Dual-Wavelength 3D Printing Breaks Free from Support Constraints.ACS central science · 2025Article
- Emerging Trends in Microfluidic Biomaterials: From Functional Design to Applications.Journal of functional biomaterials · 2025Review
- A promising breakthrough in pancreatic cancer research: The potential of spheroids as 3D models.BioImpacts : BI · 2025Review
- Multipath Projection Stereolithography for Three-Dimensional Printing Microfluidic Devices.ACS applied materials & interfaces · 2024Article
- 3D Printing in Biocatalysis and Biosensing: From General Concepts to Practical Applications.Chemistry, an Asian journal · 2024Review
- A virtual visualization method for improving the manufacturing accuracy based VPP 3D printers.Heliyon · 2024Article
- High-resolution stereolithography: Negative spaces enabled by control of fluid mechanics.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Dimension compensation of printed master molds by a desktop LCD 3D printer for high-precision microfluidic applications.Mikrochimica acta · 2024Article
- Functionality integration in stereolithography 3D printed microfluidics using a "print-pause-print" strategy.Lab on a chip · 2024Article
- Growing three-dimensional objects with light.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- A Modular and Cost-Effective Droplet Microfluidic Device for Controlled Emulsion Production.Polymers · 2024Article
- Extracellular vesicles derived from mesenchymal stem cells: the wine in Hebe's hands to treat skin aging.Precision clinical medicine · 2024Review
- Features of Vat-Photopolymerized Masters for Microfluidic Device Manufacturing.Bioengineering (Basel, Switzerland) · 2024Article
- Unpacking the packaged optical fiber bio-sensors: understanding the obstacle for biomedical application.Frontiers in bioengineering and biotechnology · 2024Review
- Review
- Biocompatible High-Resolution 3D-Printed Microfluidic Devices: Integrated Cell Chemotaxis Demonstration.Micromachines · 2023Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
While vat photopolymerization has many advantages over soft lithography in fabricating microfluidic devices, including efficiency and shape complexity, it has difficulty achieving well-controlled micrometer-sized (smaller than 100 μm) channels in the layer building direction. The considerable light penetration depth of transparent resin leads to over-curing that inevitably cures the residual resin inside flow channels, causing clogs. In this paper, a 3D printing process - in-situ transfer vat photopolymerization is reported to solve this critical over-curing issue in fabricating microfluidic devices. We demonstrate microchannels with high Z-resolution (within 10 μm level) and high accuracy (within 2 μm level) using a general method with no requirements on liquid resins such as reduced transparency nor leads to a reduced fabrication speed. Compared with all other vat photopolymerization-based techniques specialized for microfluidic channel fabrication, our universal approach is compatible with commonly used 405 nm light sources and commercial photocurable resins. The process has been verified by multifunctional devices, including 3D serpentine microfluidic channels, microfluidic valves, and particle sorting devices. This work solves a critical barrier in 3D printing microfluidic channels using the high-speed vat photopolymerization process and broadens the material options. It also significantly advances vat photopolymerization's use in applications requiring small gaps with high accuracy in the Z-direction.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.