Evidence map›Paper›PMID 35177472›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Strong influenza-induced T

Priyadharshini Devarajan, Allen M Vong, Catherine H Castonguay, Olivia Kugler-Umana, Bianca L Bautista, Michael C Jones, Karen A Kelly, Jingya Xia, Susan L Swain

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Priyadharshini DevarajanDepartment of Pathology, University of Massachusetts Medical School, Worcester, MA 01605.ORCID 0000-0003-2058-6339
Allen M VongDepartment of Pathology, University of Massachusetts Medical School, Worcester, MA 01605.
Catherine H CastonguayDepartment of Pathology, University of Massachusetts Medical School, Worcester, MA 01605.
Olivia Kugler-UmanaDepartment of Pathology, University of Massachusetts Medical School, Worcester, MA 01605.
Bianca L BautistaDepartment of Pathology, University of Massachusetts Medical School, Worcester, MA 01605.
Michael C JonesDepartment of Pathology, University of Massachusetts Medical School, Worcester, MA 01605.
Karen A KellyDepartment of Animal Medicine, University of Massachusetts Medical School, Worcester, MA 01605.
Jingya XiaDepartment of Pathology, University of Massachusetts Medical School, Worcester, MA 01605.
Susan L SwainDepartment of Pathology, University of Massachusetts Medical School, Worcester, MA 01605; susan.swain@umassmed.edu.ORCID 0000-0002-3643-8018
University of Massachusetts Chan Medical School · US

Funding

T cell memory to TB in the lungP01AI046530 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI COOPER, ANDREA M · 1999 to 2013
$22.2M
T cell and transgenic core U19AI109858 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI HUSEBY, ERIC S · 2014 to 2018
$11.9M
TRAINING IN IMMUNOLOGY (COMPETITIVE RENEWAL OF AI07439)T32AI007349 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI STERN, LAWRENCE J. · 1989 to 2024
$4.5M
Defining a memory checkpoint for CD4 T cellsR01AI118820 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI SWAIN, SUSAN L · 2015 to 2019
$2.1M
Enhancing the success of underrepresented students in the biomedical sciencesR25GM113686 · NIGMS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI LAPANE, KATE L, LEWIS, BRIAN C · 2015 to 2019
$1.7M
Training in the Molecular Basis of Autoimmunity and AutoinflammationT32AI132152 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI Katherine A. Fitzgerald, Ann Marshak-Rothstein · 2018 to 2026
$1.6M
Impact of TcR Signal Strength at the Effector Checkpoint on Protective CD4 T Cell Immunity to Influenza VirusR21AI153120 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI SWAIN, SUSAN L · 2020 to 2021
$461k
VACCINE STRATEGIES TO CIRCUMVENT AGE-ASSOCIATED IMMUNE DEFECTSR21AG058758 · NIA · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI SWAIN, SUSAN L · 2018 to 2019
$461k
Protective function of virus-induced age-associated B cellsR21AI128606 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI SWAIN, SUSAN L · 2018 to 2019
$461k
Age-Associated B Cells Specialized for Immunity to Pathogens?R21AG068313 · NIA · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI SWAIN, SUSAN L · 2021 to 2022
$461k
NIAID NIH HHS P01 AI046530NIAID NIH HHS R01 AI118820NIAID NIH HHS R21 AI128606NIAID NIH HHS R21 AI153120NIAID NIH HHS T32 AI007349NIAID NIH HHS T32 AI132152NIAID NIH HHS U19 AI109858NIA NIH HHS R21 AG058758NIA NIH HHS R21 AG068313NIGMS NIH HHS R25 GM113686
6 · The paper itself

Abstract

While influenza infection induces robust, long-lasting, antibody responses and protection, including the T follicular helper cells (T

Indexed as

AnimalsAntibodies, ViralAntibody FormationAntigensB-LymphocytesCD4-Positive T-LymphocytesFemaleGerminal CenterHumansInfluenza, HumanInfluenza VaccinesMaleMiceMice, Inbred BALB CMice, Inbred C57BLT Follicular Helper CellsAntibodies, ViralAntigensInfluenza VaccinesVaccines, AttenuatedCD4influenzaTFHT follicular helper cellsvaccination

Identifiers

PMID35177472
PMCPMC8872786
OpenAlexW4213120745

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.