Evidence map›Paper›PMID 35177442›Full record

Trial reportBMJ open2022

Assessing infant cognition in field settings using eye-tracking: a pilot cohort trial in Sierra Leone.

Jukka M Leppänen, Julius Walker Butcher, Claire Godbout, Kevin Stephenson, D Taylor Hendrixson, Stacy Griswold, Beatrice Lorge Rogers, Patrick Webb, Aminata S Koroma, Mark J Manary

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Automated Infant Eye Tracking: A Systematic Historical Review.Infancy : the official journal of the International Society on Infant Studies
    Pooled it
  2. Trial
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  8. Holistic and Analytic Attention in Infancy: A Cross-Cultural Study in Sweden and Zimbabwe.Infancy : the official journal of the International Society on Infant Studies
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Jukka M LeppänenDepartment of Psychology and Speech-Language Pathology, University of Turku, Turku, Finland jukka.leppanen@utu.fi.
Julius Walker ButcherProject Peanut Butter, Freetown, Sierra Leone.
Claire GodboutDepartment of Pediatrics, Washington University in St Louis School of Medicine, St Louis, Missouri, USA.
Kevin StephensonDepartment of Internal Medicine, Washington University in St Louis School of Medicine, St Louis, Missouri, USA.ORCID 0000-0003-4284-1062
D Taylor HendrixsonDepartment of Pediatrics, Washington University in St Louis School of Medicine, St Louis, Missouri, USA.ORCID 0000-0003-0627-3571
Stacy GriswoldFriedman School of Nutrition Science and Policy, Tufts University, Boston, Massachusetts, USA.ORCID 0000-0001-7572-3316
Beatrice Lorge RogersFriedman School of Nutrition Science and Policy, Tufts University, Boston, Massachusetts, USA.
Patrick WebbFriedman School of Nutrition Science and Policy, Tufts University, Boston, Massachusetts, USA.ORCID 0000-0002-9857-3354
Aminata S KoromaFood and Nutrition, Sierra Leone Ministry of Health and Sanitation, Freetown, Sierra Leone.
Mark J ManaryDepartment of Pediatrics, Washington University in St Louis School of Medicine, St Louis, Missouri, USA.
Washington University in St. Louis · USTufts University · USUniversity of Sierra Leone · SLUniversity of Turku · FI

Funding

Pediatric Gastroenterology Research Training ProgramT32DK077653 · NIDDK · WASHINGTON UNIVERSITY · PI PHILLIP I TARR · 2007 to 2026
$5.8M
NIDDK NIH HHS T32 DK077653
6 · The paper itself

Abstract

objectivesTo investigate the feasibility of eye-tracking-based testing of the speed of visual orienting in malnourished young children at rural clinics in Sierra Leone.

designProspective dual cohort study nested in a cluster-randomised trial.

setting8 sites participating in a cluster-randomised trial of supplementary feeding for moderate acute malnutrition (MAM).

participantsFor the MAM cohort, all infants aged 7-11 months at the eight sites were enrolled, 138 altogether. For controls, a convenience sample of all non-malnourished infants aged 7-11 months at the same sites were eligible, 60 altogether. A sample of 30 adults at the sites also underwent eye-tracking tests as a further control.

interventionsInfants with MAM were provided with supplementary feeding. OUTCOME MEASURES: The primary outcomes were feasibility and reliability of eye-tracking-based testing of saccadic reaction time (SRT). Feasibility was assessed by the percent of successful tests in the infants. Reliability was measured with intraclass correlation coefficients (ICCs). Secondary outcomes were mean SRT based on nutritional state as well as and changes in mean SRT after supplementary feeding of MAM children.

resultsInfants exhibited consistent orienting to targets on a computer screen (>95% of valid trials). Mean SRTs had moderate stability within visits (ICCs 0.60-0.69) and across the 4-week test-retest interval (0.53) in infants; the adult control group had greater SRT stability (within visit ICC=0.92). MAM infants had a trend toward higher adjusted SRT at baseline (difference=12.4 ms, 95% CI -2 to 26.9, p=0.09) and improvement in SRT 4 weeks thereafter (difference=-14 ms, 95% CI -26.2 to -1.7, p=0.025) compared with age-matched controls.

conclusionsThe results demonstrate the feasibility of eye-tracking-based testing in a resource-poor field setting and suggest eye-tracking measures have utility in the detection of group level effects of supplementary feeding.

Indexed as

CognitionEye-Tracking TechnologyAdultChildChild, PreschoolCohort StudiesHumansInfantProspective StudiesReproducibility of ResultsSierra Leonedevelopmental neurology & neurodisabilitynutritionpaediatric neurology

Identifiers

PMID35177442
PMCPMC8860005
OpenAlexW4213107204

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.