ArticleAntimicrobial resistance and infection control2022
Indwelling time of peripherally inserted central catheters and incidence of bloodstream infections in haematology patients: a cohort study.
Article in Antimicrobial resistance and infection control, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 15 citations in OpenAlex.
- Catheter-related thrombosis in cancer patients with tunnelled non-cuffed centrally inserted central catheters: a retrospective cohort study.BMC surgery · 2026Article
- Temporal and anatomic determinants of central-line-associated bloodstream infection risk in a tertiary PICU: a 3-year time-to-event and competing-risk analysis.Frontiers in pediatrics · 2026Article
- Outcomes of a bedside ultrasound-guided peripherally-inserted central catheter placement across critically-ill older patients.PloS one · 2026Article
- Balancing Costs and Clinical Outcomes: A Cost-Effectiveness Study of PICC Types Across Chinese Healthcare Settings.Journal of market access & health policy · 2025Article
- Evaluating the Cost-Effectiveness of Chlorhexidine-Coated vs. Standard Peripheral Insertion Central Catheters in Patients with Hematologic Disease: A Health Economic Analysis.International journal of environmental research and public health · 2025Article
- Antibiotic lock therapy for the treatment of peripherally inserted central venous catheter-related bloodstream infection in patients with hematological malignancies: a single center retrospective study.Annals of hematology · 2025Article
- Monitoring and Outcomes of Central Line-Associated Bloodstream Infections in a Tertiary Care Intensive Care Unit.Cureus · 2024Article
- Central venous access device terminologies, complications, and reason for removal in oncology: a scoping review.BMC cancer · 2024Article
- Central Venous Catheters versus Peripherally Inserted Central Catheters: A Comparison of Indwelling Time Resulting in Colonization by Multidrug-Resistant Pathogens.Antibiotics (Basel, Switzerland) · 2024Article
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
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Abstract
backgroundWe aimed to assess whether longer indwelling time of peripherally inserted central catheters (PICC) increases risk of central line associated bloodstream infections (CLABSI) in haematology patients.
methodsMulticentre retrospective cohort study among haematology patients receiving PICCs between 2013 and 2015. Occurrence of CLABSI based on CDC definitions was assessed. We calculated incidence rates, determined risk factors for CLABSI and used Poisson regression models to assess the risk of developing CLABSI as a function of PICC dwell time. We compared diagnoses and treatment characteristics between 2013-2015 and 2015-2020.
results455 PICCs placed in 370 patients were included, comprising 19,063 catheter days. Median indwelling time was 26 days (range 0-385) and CLABSI incidence was 4.0 per 1000 catheter days, with a median time to CLABSI of 33 days (range 18-158). Aplastic anaemia (AA) was associated with an increased risk of CLABSI; patients undergoing autologous stem cell transplantation (SCT) were less likely to develop CLABSI. In the unadjusted analysis, PICCs with an indwelling time of 15-28 days, 29-42 days, 43-56 days and > 56 days each had an increased CLABSI incidence rate ratio of 2.4 (1.2-4.8), 2.2 (0.95-5.0), 3.4 (1.6-7.5) and 1.7 (0.9-3.5), respectively, compared to PICCs in place for < 15 days. However, after adjusting for AA and SCT, there was no significant difference in incidence rates between dwell times (p 0.067).
conclusionsOur study shows that risk of CLABSI does not appear to increase with longer PICC indwelling time. Routine replacement of PICCs therefore is unlikely to prevent CLABSI in this population.
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