Evidence map›Paper›PMID 35177069›Full record

ReviewCell communication and signaling : CCS2022

Intrinsically disordered proteins play diverse roles in cell signaling.

Sarah E Bondos, A Keith Dunker, Vladimir N Uversky

Open access · goldAbstract readReview
In one paragraph

Review in Cell communication and signaling : CCS, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 104 papers.

0numbers the graph read from it
0cells of the map it votes in
104citing papers in PubMed
15.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

104 citing papers in PubMed, 201 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. SIRT1 Exon 2-Encoded IDR Gates CREB-Dependent Transcriptional Timing During Fasting.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Physics-guided design of intrinsically disordered proteins.bioRxiv : the preprint server for biology · 2026
    Article
  10. Shining light on the dark proteome with unstructural biology.Current research in structural biology · 2026
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

44 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Sarah E BondosDepartment of Molecular and Cellular Medicine, Texas A&M Health Science Center, College Station, TX, 77843, USA. bondos@tamu.edu.ORCID 0000-0002-9673-4169
A Keith DunkerCenter for Computational Biology and Bioinformatics, Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.
Vladimir N UverskyDepartment of Molecular Medicine and USF Health Byrd Alzheimer's Research Institute, Morsani College of Medicine, University of South Florida, Tampa, FL, 33612, USA.
Indiana University School of MedicineTexas A&M Health Science Center · USUniversity of South Florida · US

Funding

Computational design of specific binding proteins using Leave-One-OutR01GM099827 · NIGMS · RENSSELAER POLYTECHNIC INSTITUTE · PI BONDOS, SARAH E, BYSTROFF, CHRISTOPHER · 2012 to 2021
$2.9M
Controlling tau toxicity from inside and outside of neuronsRF1AG055088 · NIA · UNIVERSITY OF SOUTH FLORIDA · PI BICKFORD, PAULA C, BLAIR, LAURA J · 2017 to 2017
$2.3M
NIA NIH HHS RF1 AG055088NIGMS NIH HHS R01 GM099827
6 · The paper itself

Abstract

Signaling pathways allow cells to detect and respond to a wide variety of chemical (e.g. Ca

Indexed as

Intrinsically Disordered ProteinsAnimalsCell CommunicationSignal TransductionIntrinsically Disordered ProteinsCell signal amplificationDifferentiationIntegrationPropagationSpecificity

Identifiers

PMID35177069
PMCPMC8851865
OpenAlexW4212940766

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.