Evidence map›Paper›PMID 35177020›Full record

ArticleBMC medical imaging2022

The application research of AI image recognition and processing technology in the early diagnosis of the COVID-19.

Wenyu Chen, Ming Yao, Zhenyu Zhu, Yanbao Sun, Xiuping Han

Open access · goldAbstract read
In one paragraph

Article in BMC medical imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Wenyu Chen *Department of Respiration, Affiliated Hospital of Jiaxing University, Jiaxing, China.
Ming Yao *Department of Pain Medicine Center, Affiliated Hospital of Jiaxing University, Jiaxing, China.
Zhenyu Zhu *Yangtze Delta Region Institute of Tsinghua University, Zhejiang, No. 705, Asia Pacific Road, Nanhu District, Jiaxing, 314006, Zhejiang, China.
Yanbao SunRadiology Department, Affiliated Hospital of Jiaxing University, No. 1882 Zhonghuan South Road, Jiaxing, 314000, China. 552143053@qq.com.
Xiuping HanYangtze Delta Region Institute of Tsinghua University, Zhejiang, No. 705, Asia Pacific Road, Nanhu District, Jiaxing, 314006, Zhejiang, China. hanxiuping@tsinghua-zj.edu.cn.
Jiaxing University · CNTsinghua University · CN

Funding

A Project Supported by Scientific Research Fund of Zhejiang Provincial Education Department Y202043729Jiaxing Fight Novel Coronavirus Pneumonia Emergency Technology Attack Special Project in 2020 2020GZ30001Key Discipline of Jiaxing Respiratory Medicine Construction Project 2019-zc-04
6 · The paper itself

Abstract

backgroundThis study intends to establish a combined prediction model that integrates the clinical symptoms,the lung lesion volume, and the radiomics features of patients with COVID-19, resulting in a new model to predict the severity of COVID-19.

methodsThe clinical data of 386 patients with COVID-19 at several hospitals, as well as images of certain patients during their hospitalization, were collected retrospectively to create a database of patients with COVID-19 pneumonia. The contour of lungs and lesion locations may be retrieved from CT scans using a CT-image-based quantitative discrimination and trend analysis method for COVID-19 and the Mask R-CNN deep neural network model to create 3D data of lung lesions. The quantitative COVID-19 factors were then determined, on which the diagnosis of the development of the patients' symptoms could be established. Then, using an artificial neural network, a prediction model of the severity of COVID-19 was constructed by combining characteristic imaging features on CT slices with clinical factors. ANN neural network was used for training, and tenfold cross-validation was used to verify the prediction model. The diagnostic performance of this model is verified by the receiver operating characteristic (ROC) curve.

resultsCT radiomics features extraction and analysis based on a deep neural network can detect COVID-19 patients with an 86% sensitivity and an 85% specificity. According to the ROC curve, the constructed severity prediction model indicates that the AUC of patients with severe COVID-19 is 0.761, with sensitivity and specificity of 79.1% and 73.1%, respectively.

conclusionsThe combined prediction model for severe COVID-19 pneumonia, which is based on deep learning and integrates clinical aspects, pulmonary lesion volume, and radiomics features of patients, has a remarkable differential ability for predicting the course of disease in COVID-19 patients. This may assist in the early prevention of severe COVID-19 symptoms.

Indexed as

Artificial IntelligenceAdultAgedCOVID-19Early DiagnosisFemaleHumansMaleMiddle AgedRetrospective StudiesArtificial intelligenceComputed tomographyCOVID-19Diagnosis

Identifiers

PMID35177020
PMCPMC8851724
OpenAlexW4212865776

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.