Evidence map›Paper›PMID 35176894›Full record

ArticleCartilage

Correlation of the Histological ICRS II Score and the 3D MOCART Score for the Analysis of Aged Osteochondral Regenerates in a Large Animal Model.

J C Schagemann, L Galle, J Gille, A Frydrychowicz, G Welsch, G Salzmann, A Paech, H Mittelstaedt

Abstract read
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Article in Cartilage. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

J C SchagemannMedicine Section, University of Lübeck, Lübeck, Germany.ORCID 0000-0002-5122-5897
L GalleMedicine Section, University of Lübeck, Lübeck, Germany.
J GilleMedicine Section, University of Lübeck, Lübeck, Germany.
A FrydrychowiczDepartment of Radiology, University Medical Center Schleswig-Holstein, Lübeck, Germany.
G WelschUKE Athleticum-Center for Athletic Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
G SalzmannGelenkzentrum Rhein-Main, Frankfurt, Germany.
A PaechDepartment for Orthopaedic and Trauma Surgery, University Medical Center Schleswig-Holstein, Lübeck, Germany.
H MittelstaedtDepartment for Orthopaedic and Trauma Surgery, University Medical Center Schleswig-Holstein, Lübeck, Germany.ORCID 0000-0002-8199-5390

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveReliable outcome measures are essential to predict the success of cartilage repair techniques. Histology is probably the gold standard, but magnetic resonance imaging (MRI) has the potential to decrease the need for invasive histological biopsies. The 3D magnetic resonance observation of cartilage repair tissue (MOCART) score is a reliable yet elaborate tool. Moreover, literature is controversial concerning the correlation of histology and MRI.

designTo test the applicability of the International Cartilage Regeneration and Joint Preservation Society (ICRS) II and MOCART 3D score for the evaluation of aged osteochondral regenerates in a large animal model, and to identify correlating histological and MRI parameters. Osteochondral defects in medial femoral condyles of

resultsWe found a statistically significant correlation of all histological parameters. MRI parameters reflecting "overall" assessments had very strong inter-rater correlations. Statistically significant strong correlations were found for the MRI parameters

conclusionsThe ICRS II and the 3D MOCART score are applicable to aged osteochondral regenerates. Prior training on the scoring systems is essential. Select MRI and histological parameters correlate; however, the only statistically significant correlation was found for

Indexed as

Cartilage, ArticularIntra-Articular FracturesAnimalsDisease Models, AnimalKnee JointMagnetic Resonance ImagingReproducibility of ResultsSheepanimal modelcartilage repairhistological scoringmagnetic resonance imagingoutcome measures

Identifiers

PMID35176894
PMCPMC9137325

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.