Evidence map›Paper›PMID 35176752›Full record

ArticleCerebral cortex (New York, N.Y. : 1991)2022

Frontal eye fields in macaque monkeys: prefrontal and premotor contributions to visually guided saccades.

Kaleb A Lowe, Wolf Zinke, Joshua D Cosman, Jeffrey D Schall

Open access · greenAbstract read
In one paragraph

Article in Cerebral cortex (New York, N.Y. : 1991), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Visuomotor flexibility is embedded in the topography of frontal cortex.bioRxiv : the preprint server for biology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Kaleb A LoweDepartment of Psychology, Vanderbilt University, Center for Integrative and Cognitive Neuroscience, Vanderbilt Vision Research Center.ORCID 0000-0001-5188-3964
Wolf ZinkeDepartment of Psychology, Vanderbilt University, Center for Integrative and Cognitive Neuroscience, Vanderbilt Vision Research Center.
Joshua D CosmanDepartment of Psychology, Vanderbilt University, Center for Integrative and Cognitive Neuroscience, Vanderbilt Vision Research Center.
Jeffrey D SchallDepartment of Psychology, Vanderbilt University, Center for Integrative and Cognitive Neuroscience, Vanderbilt Vision Research Center.
Vanderbilt University · US

Funding

Shop Module CoreP30EY008126 · NEI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Kevin L Schey · 1989 to 2026
$19.6M
SACCADE TARGET SELECTION-FRONTAL CORTEXR01EY008890 · NEI · VANDERBILT UNIVERSITY · PI WOODMAN, GEOFFREY F · 1991 to 2018
$7.4M
Research Project: Sensory and Multisensory Contributions to AutismU54HD083211 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI DYKENS, ELISABETH MAY · 2015 to 2019
$7.1M
NEI NIH HHS P30 EY008126NEI NIH HHS R01 EY008890NICHD NIH HHS U54 HD083211NICHD NIH HHS U54-HD083211
6 · The paper itself

Abstract

Neuronal spiking was sampled from the frontal eye field (FEF) and from the rostral part of area 6 that reaches to the superior limb of the arcuate sulcus, dorsal to the arcuate spur when present (F2vr) in macaque monkeys performing memory-guided saccades and visually guided saccades for visual search. Neuronal spiking modulation in F2vr resembled that in FEF in many but not all respects. A new consensus clustering algorithm of neuronal modulation patterns revealed that F2vr and FEF contain a greater variety of modulation patterns than previously reported. The areas differ in the proportions of visuomotor neuron types, the proportions of neurons discriminating a target from distractors during visual search, and the consistency of modulation patterns across tasks. However, between F2vr and FEF we found no difference in the magnitude of delay period activity, the timing of the peak discharge rate relative to saccades, or the time of search target selection. The observed similarities and differences between the 2 cortical regions contribute to other work establishing the organization of eye fields in the frontal lobe and may help explain why FEF in monkeys is identified within granular prefrontal area 8 but in humans is identified within agranular premotor area 6.

Indexed as

Motor CortexSaccadesAnimalsFrontal LobeHaplorhiniHumansMacacaVisual Fieldscortical areafrontal eye fieldgaze controlpremotor cortexvisual search

Identifiers

PMID35176752
PMCPMC9989351
OpenAlexW4210399026

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.