Evidence map›Paper›PMID 35176286›Full record

ReviewNeuropharmacology2022

Noradrenergic circuits and signaling in substance use disorders.

Anthony M Downs, Zoe A McElligott

Open access · greenAbstract readReview
In one paragraph

Review in Neuropharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 38 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Anthony M DownsBowles Center for Alcohol Studies, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA. Electronic address: Anthony_downs@med.unc.edu.
Zoe A McElligottBowles Center for Alcohol Studies, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA; Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA. Electronic address: zoemce@email.unc.edu.
University of North Carolina at Chapel Hill · US

Funding

Supplement to Molecular and Cellular Studies on Alcohol's ActionsT32AA007573 · NIAAA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI FULTON T CREWS, Thomas L. Kash · 1997 to 2026
$9.3M
Probing Ethanol Induced Acceleration of Hindbrain and Amygdalar Pathology in an Alzheimer’s Disease ModelU01AA020911 · NIAAA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Thomas L. Kash, Zoe Anastasia McElligott · 2012 to 2026
$5.8M
Noradrenergic Plasticity in Opioid WithdrawalR01DA049261 · NIDA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MCELLIGOTT, ZOE ANASTASIA · 2020 to 2024
$2.0M
NIAAA NIH HHS T32 AA007573NIAAA NIH HHS U01 AA020911NIDA NIH HHS R01 DA049261
6 · The paper itself

Abstract

The central noradrenergic system innervates almost all regions of the brain and, as such, is well positioned to modulate many neural circuits implicated in behaviors and physiology underlying substance use disorders. Ample pharmacological evidence demonstrates that α

Indexed as

NorepinephrineSubstance-Related DisordersBrainDrug-Seeking BehaviorHumansLocus CoeruleusReceptors, Adrenergic, betaNorepinephrineReceptors, Adrenergic, betaAlcoholLocus coeruleusNorepinephrineNucleus of the tractus solitariusOpioidsPsychostimulants

Identifiers

PMID35176286
PMCPMC9498225
OpenAlexW4213249713

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.