Evidence map›Paper›PMID 35176258›Full record

ArticleThe Annals of thoracic surgery2022

Advancing Quality Metrics for Durable Left Ventricular Assist Device Implant: Analysis of the Society of Thoracic Surgeons Intermacs Database.

Michael J Pienta, Xiaoting Wu, Thomas M Cascino, Alexander A Brescia, Ashraf Abou El Ela, Min Zhang, Jeffrey S McCullough, Supriya Shore, Keith D Aaronson, Michael P Thompson and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in The Annals of thoracic surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Incompleteness of health-related quality of life assessments before left ventricular assist device implant: A novel quality metric.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2022
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Michael J PientaDepartment of Cardiac Surgery, Michigan Medicine, Ann Arbor, Michigan. Electronic address: mpienta@med.umich.edu.
Xiaoting WuDepartment of Cardiac Surgery, Michigan Medicine, Ann Arbor, Michigan.
Thomas M CascinoDivision of Cardiovascular Medicine, Michigan Medicine, Ann Arbor, Michigan.
Alexander A BresciaDepartment of Cardiac Surgery, Michigan Medicine, Ann Arbor, Michigan.
Ashraf Abou El ElaDepartment of Cardiac Surgery, Michigan Medicine, Ann Arbor, Michigan.
Min ZhangDepartment of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, Michigan.
Jeffrey S McCulloughDepartment of Health Management and Policy, School of Public Health, University of Michigan, Ann Arbor, Michigan.
Supriya ShoreDivision of Cardiovascular Medicine, Michigan Medicine, Ann Arbor, Michigan.
Keith D AaronsonDivision of Cardiovascular Medicine, Michigan Medicine, Ann Arbor, Michigan.
Michael P ThompsonDepartment of Cardiac Surgery, Michigan Medicine, Ann Arbor, Michigan.
Francis D PaganiDepartment of Cardiac Surgery, Michigan Medicine, Ann Arbor, Michigan.
Donald S LikoskyDepartment of Cardiac Surgery, Michigan Medicine, Ann Arbor, Michigan.
Michigan Congestive Heart Failure Investigators
Michigan Medicine · USUniversity of Michigan–Ann Arbor · US

Funding

Novel Assessments of Technical and Non-Technical Cardiac Surgery QualityR01HL146619 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LIKOSKY, DONALD S, PAGANI, FRANCIS D · 2020 to 2024
$3.4M
Understanding and Addressing Variation in Healthcare-Associated Infections After Durable Ventricular Assist Device TherapyR01HS026003 · AHRQ · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LIKOSKY, DONALD S · 2018 to 2022
$2.3M
AHRQ HHS K01 HS027830AHRQ HHS R01 HS026003NHLBI NIH HHS R01 HL146619
6 · The paper itself

Abstract

backgroundPatients undergoing left ventricular assist device (LVAD) implantation are at risk for death and postoperative adverse outcomes. Interhospital variability and concordance of quality metrics were assessed using the Society of Thoracic Surgeons Interagency Registry for Mechanically Assisted Circulatory Support (Intermacs).

methodsA total of 22 173 patients underwent primary, durable LVAD implantation across 160 hospitals from 2012 to 2020, excluding hospitals performing <10 implant procedures. Observed and risk-adjusted operative mortality rates were calculated for each hospital. Outcomes included operative and 90-day mortality, a composite of adverse events (operative mortality, bleeding, stroke, device malfunction, renal dysfunction, respiratory failure), and secondarily failure to rescue. Rates are presented as median (interquartile range [IQR]). Hospital performance was evaluated using observed-to-expected (O/E) ratios for mortality and the composite outcome.

resultsInterhospital variability existed in observed (median, 7.2% [IQR, 5.1%-9.6%]) mortality. The rates of adverse events varied across hospitals: major bleeding, 15.6% (IQR, 11.4%-22.4%); stroke, 3.1% (IQR, 1.6%-4.7%); device malfunction, 2.4% (IQR, 0.8%-3.7%); respiratory failure, 10.5% (IQR, 4.6%-15.7%); and renal dysfunction, 6.4% (IQR, 3.2%-9.6%). The O/E ratio for operative mortality varied from 0.0 to 6.1, whereas the O/E ratio for the composite outcome varied from 0.28 to 1.99. Hospital operative mortality O/E ratios were more closely correlated with the 90-day mortality O/E ratio (r = 0.74) than with the composite O/E ratio (r = 0.12).

conclusionsThis study reported substantial interhospital variability in performance for hospitals implanting durable LVADs. These findings support the need to (1) report hospital-level performance (mortality, composite) and (2) undertake benchmarking activities to reduce unwarranted variability in outcomes.

Indexed as

Heart-Assist DevicesHeart FailureKidney DiseasesRespiratory InsufficiencyStrokeSurgeonsBenchmarkingFemaleHumansMaleRegistriesRetrospective StudiesTreatment Outcome

Identifiers

PMID35176258
PMCPMC9035070
OpenAlexW4212856065

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.