Evidence map›Paper›PMID 35176215›Full record

ArticleJournal of the Royal Society of Medicine2022

Use of lifestyle interventions in primary care for individuals with newly diagnosed hypertension, hyperlipidaemia or obesity: a retrospective cohort study.

Julia M Lemp, Meghana Prasad Nuthanapati, Till W Bärnighausen, Sebastian Vollmer, Pascal Geldsetzer, Anant Jani

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the Royal Society of Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.

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  15. Moral distress and the importance of data.Journal of the Royal Society of Medicine · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 4 countries.

Julia M LempHeidelberg Institute of Global Health, Heidelberg University and University Hospital, 69120 Heidelberg, Germany.ORCID 0000-0002-1524-3641
Meghana Prasad NuthanapatiDepartment of Economics and Centre for Modern Indian Studies, University of Goettingen, 37073 Göttingen, Germany.
Till W BärnighausenHeidelberg Institute of Global Health, Heidelberg University and University Hospital, 69120 Heidelberg, Germany.
Sebastian VollmerDepartment of Economics and Centre for Modern Indian Studies, University of Goettingen, 37073 Göttingen, Germany.ORCID 0000-0002-7863-0462
Pascal GeldsetzerHeidelberg Institute of Global Health, Heidelberg University and University Hospital, 69120 Heidelberg, Germany.
Anant JaniHeidelberg Institute of Global Health, Heidelberg University and University Hospital, 69120 Heidelberg, Germany.ORCID 0000-0002-7046-6768
Heidelberg University · DEUniversity of Göttingen · DEHarvard University · US

Funding

Institutional Career Development Core (KL2)KL2TR003143 · NCATS · STANFORD UNIVERSITY · PI ASCH, STEVEN M. · 2019 to 2023
$8.7M
NCATS NIH HHS KL2 TR003143
6 · The paper itself

Abstract

objectiveLifestyle interventions can be efficacious in reducing cardiovascular disease risk factors and are recommended as first-line interventions in England. However, recent information on the use of these interventions in primary care is lacking. We investigated for how many patients with newly diagnosed hypertension, hyperlipidaemia or obesity, lifestyle interventions were recorded in their primary care electronic health record.

designA retrospective cohort study.

settingEnglish primary care, using UK Clinical Practice Research Datalink.

participantsA total of 770,711 patients who were aged 18 years or older and received a new diagnosis of hypertension, hyperlipidaemia or obesity between 2010 and 2019.

main outcome measuresRecord of lifestyle intervention and/or medication in 12 months before to 12 months after initial diagnosis (2-year timeframe).

resultsAnalyses show varying results across conditions: While 55.6% (95% CI 54.9-56.4) of individuals with an initial diagnosis of hypertension were recorded as having lifestyle support (lifestyle intervention or signposting) within the 2-year timeframe, this number was reduced to 45.2% (95% CI 43.8-46.6) for hyperlipidaemia and 52.6% (95% CI 51.1-54.1) for obesity. For substantial proportions of individuals neither lifestyle support nor medication (hypertension: 12.2%, 95% CI 11.9-12.5; hyperlipidaemia: 32.2%, 95% CI 31.2-33.3; obesity: 43.9%, 95% CI 42.3-45.4) were recorded. Sensitivity analyses confirm that limited proportions of patients had lifestyle support recorded in their electronic health record before they were first prescribed medication (diagnosed and undiagnosed), ranging from 12.1% for hypertension to 19.7% for hyperlipidaemia, and 19.5% for obesity (23.4% if restricted to Orlistat).

conclusionsLimited evidence of lifestyle support for individuals with cardiovascular risk factors (hypertension, hyperlipidaemia, obesity) recommended by national guidelines in England may stem from poor recording in electronic health records but may also represent missed opportunities. Given the link between progression to cardiovascular disease and modifiable lifestyle factors, early support for patients to manage their conditions through non-pharmaceutical interventions by establishing lifestyle modification as first-line treatment is crucial.

Indexed as

Cardiovascular DiseasesHyperlipidemiasHypertensionHumansLife StyleObesityPrimary Health CareRetrospective Studiescardiovascular diseaseDisease preventionlifestyle interventionprimary care

Identifiers

PMID35176215
PMCPMC9340092
OpenAlexW4213244993

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.