Evidence map›Paper›PMID 35175950›Full record

ArticleCancer nursing

Adherence to Analgesics Among Outpatients Seriously Ill With Cancer.

Stephen J Stapleton, Brenda W Dyal, Andrew D Boyd, Marie L Suarez, Miriam O Ezenwa, Yingwei Yao, Diana J Wilkie

Abstract read
In one paragraph

Article in Cancer nursing. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Stephen J StapletonAuthor Affiliations: Department of Nursing, Concordia College (Dr Stapleton), Moorhead, Minnesota; Department of Biobehavioral Nursing Science, College of Nursing, University of Florida (Drs Dyal, Ezenwa, Yao, and Wilkie), Gainesville; and Department of Biomedical and Health Information Sciences, College of Applied Health Sciences (Dr Boyd), and Department of Biobehavioral Nursing Science, College of Nursing (Dr Suarez), University of Illinois Chicago.
Brenda W Dyal
Andrew D Boyd
Marie L Suarez
Miriam O Ezenwa
Yingwei Yao
Diana J Wilkie

Funding

Tissue Modeling & Drug Development Shared Resources CoreU54CA233444 · NCI · UNIVERSITY OF FLORIDA · PI Chanita A. Hughes-Halbert, Tianze Jiao · 2018 to 2026
$12.1M
Tissue Modeling CoreU54CA233465 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Bodour Salhia · 2018 to 2026
$11.9M
Tissue Modeling CoreU54CA233396 · NCI · FLORIDA AGRICULTURAL AND MECHANICAL UNIV · PI Sandra G Suther · 2018 to 2026
$9.8M
Nursing and Health Research Informatics CoreP30NR010680 · NINR · UNIVERSITY OF ILLINOIS AT CHICAGO · PI FOREMAN, MARQUIS D · 2007 to 2011
$2.4M
Effects &Costs of Massage in Hospice Cancer PatientsR01NR009092 · NINR · UNIVERSITY OF ILLINOIS AT CHICAGO · PI WILKIE, DIANA J · 2005 to 2009
$1.8M
NCI NIH HHS U54 CA233396NCI NIH HHS U54 CA233444NCI NIH HHS U54 CA233465NINR NIH HHS P30 NR010680NINR NIH HHS R01 NR009092
6 · The paper itself

Abstract

backgroundAdherence to prescribed analgesics for patients seriously ill with cancer pain is essential for comfort.

objectiveThe objective of this study was to determine the analgesic adherence in seriously ill patients with cancer and its association with clinical and demographic characteristics.

methodsThis is a cross-sectional study. At home, 202 patients with cancer (mean age, 59.9 ± 14.2 years; 58% female, 48% Black, and 42% White) admitted to hospice/palliative care completed measures on a pen tablet: PAIN Report It, Symptom Distress Scale, mood state item, Pittsburgh Sleep Quality Index item, and Pain Management Index.

resultsThe mean current pain intensity was 4.4 ± 2.9, and the mean worst pain in the past 24 hours was 7.2 ± 2.7. More than one-half of participants were not satisfied with their pain level (54%) and reported their pain was more intense than they wanted to tolerate for 18 hours or longer in the last 24 hours (51%). Only 12% were not prescribed analgesics appropriate for the intensity of their pain. Adherence rates were variable: nonsteroidal anti-inflammatory drugs (0.63 ± 0.50), adjuvants (0.93 ± 0.50), World Health Organization step 2 opioids (0.63 ± 0.49), and step 3 opioids (0.80 ± 0.40). With setting/clinical/demographic variables in the model, dose intervals of less than 8 hours were associated with less adherence ( P < .001).

conclusionLittle progress has been made toward improving analgesic adherence even in settings providing analgesics without cost. Research focused on targeting analgesic dose intervals and barriers not related to cost is needed. IMPLICATION FOR PRACTICE: Dose intervals of 8 hours or longer were significantly associated with higher adherence rates; therefore, use of longer-acting analgesics is one strategy to improve pain control at the end of life.

Indexed as

Cancer PainNeoplasmsAgedAnalgesicsAnalgesics, OpioidCross-Sectional StudiesFemaleHumansMaleMiddle AgedOutpatientsPainAnalgesicsAnalgesics, Opioid

Identifiers

PMID35175950
PMCPMC9378770

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.