Evidence map›Paper›PMID 35175880›Full record

ReviewExpert review of respiratory medicine2022

Tuberculosis in children with severe acute malnutrition.

Bryan J Vonasek, Kendra K Radtke, Paula Vaz, W Chris Buck, Chishala Chabala, Eric D McCollum, Olivier Marcy, Elizabeth Fitzgerald, Alexander Kondwani, Anthony J Garcia-Prats

Erratum issuedAbstract readReview
In one paragraph

Review in Expert review of respiratory medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Article
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  4. High prevalence of TB in children less than 5 years old hospitalised with severe acute malnutrition.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Bryan J VonasekDepartment of Pediatrics, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0002-5657-0980
Kendra K RadtkeDepartment of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, California, USA.
Paula VazFundação Ariel Glaser, Maputo, Mozambique.
W Chris BuckDavid Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA.
Chishala ChabalaChildren's Hospital, University Teaching Hospitals, Lusaka, Zambia.
Eric D McCollumGlobal Program in Respiratory Sciences, Eudowood Division of Pediatric Respiratory Sciences, Department of Pediatrics, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Olivier MarcyUniversity of Bordeaux, Inserm, French National Research Institute for Sustainable Development (Ird), Bordeaux, France.
Elizabeth FitzgeraldDepartment of Pediatrics, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA.
Alexander KondwaniCentre of Excellence for Nutrition, North West University, Potchefstroom, South Africa.
Anthony J Garcia-PratsDepartment of Pediatrics, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0002-9280-1950

Funding

PHARMACEUTICAL SCIENCES AND PHARMACOGENOMICST32GM007175 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI AHITUV, NADAV, KROETZ, DEANNA L · 1985 to 2021
$7.1M
Microbial Pathogenesis &Host Responses Training ProgramT32AI055397 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI KLEIN, BRUCE STEVEN · 2003 to 2024
$5.5M
NIAID NIH HHS T32 AI055397NIGMS NIH HHS T32 GM007175
6 · The paper itself

Abstract

introductionWith growing attention globally to the childhood tuberculosis epidemic after decades of neglect, and with the burden of severe acute malnutrition (SAM) remaining unacceptably high worldwide, the collision of these two diseases is an important focus for improving child health. AREAS COVERED: This review describes the clinical and public health implications of the interplay between tuberculosis and SAM, particularly for children under the age of five, and identifies priority areas for improved programmatic implementation and future research. We reviewed the literature on PubMed and other evidence known to the authors published until August 2021 relevant to this topic. EXPERT OPINION: To achieve the World Health Organization's goal of eliminating deaths from childhood tuberculosis and to improve the abysmal outcomes for children with SAM, further research is needed to 1) better understand the epidemiologic connections between child tuberculosis and SAM, 2) improve case finding of tuberculosis in children with SAM, 3) assess unique treatment considerations for tuberculosis when children also have SAM, and 4) ensure tuberculosis and SAM are strongly addressed in decentralized, integrated models of providing primary healthcare to children.

Indexed as

Severe Acute MalnutritionTuberculosisChildGlobal HealthHumansInfantChildhood tuberculosissevere acute malnutritiontuberculosis

Identifiers

PMID35175880
PMCPMC9280657

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.