Evidence map›Paper›PMID 35175847›Full record

ArticleCirculation research2022

Heart Failure Subtypes and Cardiomyopathies in Women.

Ersilia M DeFilippis, Anna Beale, Trejeeve Martyn, Anubha Agarwal, Uri Elkayam, Carolyn S P Lam, Eileen Hsich

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in Circulation research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
9.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 61 citations in OpenAlex.

  1. Article
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  12. Sex differences in atrial fibrillation ablation outcomes in patients with heart failure.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2024
    Article
  13. Article
  14. Sex-specific patterns of donor-derived cell-free DNA in heart transplant rejection: An analysis from the Genomic Research Alliance for Transplantation (GRAfT).The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2024
    Article
  15. Review
  16. Article
  17. Article
  18. Sex Disparities in Cardiovascular Disease.Methodist DeBakey cardiovascular journal · 2024
    Review
  19. Cardiomyopathies in Women.Methodist DeBakey cardiovascular journal · 2024
    Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 3 countries.

Ersilia M DeFilippisDivision of Cardiology, Columbia University Irving Medical Center (E.M.D.).ORCID 0000-0002-0493-1326
Anna BealeDepartment of Cardiology, Alfred Hospital, Melbourne, Australia (A.B.).
Trejeeve MartynDepartment of Cardiology, Cleveland Clinic, Ohio (T.M., E.H.).
Anubha AgarwalNorthwestern University Feinberg School of Medicine (A.A.).ORCID 0000-0002-7090-5601
Uri ElkayamDivision of Cardiovascular Medicine, Keck School of Medicine, University of Southern California (U.E.).ORCID 0000-0003-3150-5709
Carolyn S P LamNational Heart Centre Singapore and Duke-National University of Singapore (C.S.P.L.).ORCID 0000-0003-1903-0018
Eileen HsichDepartment of Cardiology, Cleveland Clinic, Ohio (T.M., E.H.).ORCID 0000-0001-6420-0480
Cleveland Clinic · USColumbia University Irving Medical Center · USNational University Heart Centre Singapore · SGNorthwestern University · USThe Alfred Hospital · AUUniversity of Southern California · US

Funding

Impact of Disparities Affecting Survival among Advanced Heart Failure Patients and Transplant RecipientsR01HL141892 · NHLBI · CLEVELAND CLINIC LERNER COM-CWRU · PI HSICH, EILEEN MICHELLE, ISHWARAN, HEMANT · 2018 to 2021
$2.8M
NHLBI NIH HHS R01 HL141892
6 · The paper itself

Abstract

Heart failure affects over 2.6 million women and 3.4 million men in the United States with known sex differences in epidemiology, management, response to treatment, and outcomes across a wide spectrum of cardiomyopathies that include peripartum cardiomyopathy, hypertrophic cardiomyopathy, stress cardiomyopathy, cardiac amyloidosis, and sarcoidosis. Some of these sex-specific considerations are driven by the cellular effects of sex hormones on the renin-angiotensin-aldosterone system, endothelial response to injury, vascular aging, and left ventricular remodeling. Other sex differences are perpetuated by implicit bias leading to undertreatment and underrepresentation in clinical trials. The goal of this narrative review is to comprehensively examine the existing literature over the last decade regarding sex differences in various heart failure syndromes from pathophysiological insights to clinical practice.

Indexed as

Sex CharacteristicsAngiotensin-Converting Enzyme InhibitorsAngiotensin Receptor AntagonistsCardiac Resynchronization TherapyCardiomyopathiesFemaleGonadal Steroid HormonesHeart FailureHumansStroke VolumeVentricular RemodelingAngiotensin-Converting Enzyme InhibitorsAngiotensin Receptor AntagonistsGonadal Steroid Hormonescardiomyopathiesestrogensheart failureperipartumwomen

Identifiers

PMID35175847
PMCPMC10361647
OpenAlexW4213113600

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.