ReviewCirculation research2022
Pregnancy and Reproductive Risk Factors for Cardiovascular Disease in Women.
Review in Circulation research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 155 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
155 citing papers in PubMed, 5 syntheses or guidelines pooled it, 298 citations in OpenAlex.
- Female infertility and long-term cardiovascular risk: a systematic review and meta-analysis.Endocrine · 2026Pooled it
- National Heart Center/Saudi Heart Association 2025 Guidelines for Cardiovascular Diseases Prevention and Risk Assessment.Saudi medical journal · 2026Guideline
- Brazilian Guideline on Menopausal Cardiovascular Health - 2024.Arquivos brasileiros de cardiologia · 2024Guideline
- Contraceptive counselling and uptake of contraception among women with cardiovascular diseases: a systematic review and meta-analysis.Clinical research in cardiology : official journal of the German Cardiac Society · 2024Pooled it
- Polygenic prediction of preeclampsia and gestational hypertension.Nature medicine · 2023Pooled it
- Premature coronary artery disease in women: sex-specific risk factors, pathogenetic mechanisms and clinical implications.Annals of medicine · 2026Review
- Obesity, incretin-based therapies, and cardiovascular disease in women.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2026Review
- HomeSafe: Postpartum Hypertensive Care Enabled by Electronic Health Record Digital Blood Pressure Capture and Population Health Management.American journal of perinatology · 2026Article
- Implementation strategies: bridging obstetrics and long-term care.American journal of obstetrics & gynecology MFM · 2026Review
- Associations of Reproductive Factors With Hypertension Prevalence and Blood Pressure Levels in Female Nurses: A Cross-Sectional Study.Journal of clinical hypertension (Greenwich, Conn.) · 2026Article
- Coronary Artery Disease in Women: Sex-Specific Pathophysiology, Risk Factors, Clinical Presentation and Management.Medicina (Kaunas, Lithuania) · 2026Review
- Patient feedback on an educational tool to empower patients after hypertensive pregnancy.Pregnancy (Hoboken, N.J.) · 2026Article
- Discordance Between Perceived Risk and Cardiovascular Health in Women of Reproductive Age.JACC. Advances · 2026Article
- Cardiovascular Changes in Women Undergoing Medicated and Natural Frozen Embryo Transfer Cycles: A Prospective Observational Cohort Study.Journal of clinical medicine · 2026Article
- Early Pregnancy Central Obesity and Risk of Prenatal and Postpartum Diabetes and Hypertensive Disorders.Diabetes care · 2026Article
- Psychological Health, Polysocial Risk, and Cardiovascular Health Among Women of Reproductive Age.JACC. Advances · 2026Article
- The gut microbiota and metabolomics in the pathogenesis of type 2 diabetes mellitus combined with coronary atherosclerotic heart disease.Scientific reports · 2026Article
- Reproductive risk factors and prevalence of cardiovascular-kidney-metabolic syndrome among young women.American journal of preventive cardiology · 2026Article
- Perceived Risk Perception of Future Cardiovascular Disease and Diabetes in the Postpartum Period.Journal of personalized medicine · 2026Article
- Community based interventions for the primary prevention of cardiovascular disease in women living in rural, regional and remote areas: a scoping review.BMC health services research · 2026Article
95 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 10 institutions in 3 countries.
Funding
Abstract
Beyond conventional risk factors for cardiovascular disease, women face an additional burden of sex-specific risk factors. Key stages of a woman's reproductive history may influence or reveal short- and long-term cardiometabolic and cardiovascular trajectories. Early and late menarche, polycystic ovary syndrome, infertility, adverse pregnancy outcomes (eg, hypertensive disorders of pregnancy, gestational diabetes, preterm delivery, and intrauterine growth restriction), and absence of breastfeeding are all associated with increased future cardiovascular disease risk. The menopause transition additionally represents a period of accelerated cardiovascular disease risk, with timing (eg, premature menopause), mechanism, and symptoms of menopause, as well as treatment of menopause symptoms, each contributing to this risk. Differences in conventional cardiovascular disease risk factors appear to explain some, but not all, of the observed associations between reproductive history and later-life cardiovascular disease; further research is needed to elucidate hormonal effects and unique sex-specific disease mechanisms. A history of reproductive risk factors represents an opportunity for comprehensive risk factor screening, refinement of cardiovascular disease risk assessment, and implementation of primordial and primary prevention to optimize long-term cardiometabolic health in women.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.