Evidence map›Paper›PMID 35175744›Full record

ArticleEnvironmental science & technology2022

Utilizing Pine Needles to Temporally and Spatially Profile Per- and Polyfluoroalkyl Substances (PFAS).

Kaylie I Kirkwood, Jonathon Fleming, Helen Nguyen, David M Reif, Erin S Baker, Scott M Belcher

Abstract read
In one paragraph

Article in Environmental science & technology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

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  12. Feasibility of IR-MALDESI Mass Spectrometry Imaging of PFAS.Journal of mass spectrometry : JMS · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kaylie I KirkwoodNorth Carolina State University, Department of Chemistry, Raleigh, North Carolina 27607, United States.ORCID 0000-0003-3248-820X
Jonathon FlemingNorth Carolina State University, Department of Biological Sciences, Raleigh, North Carolina 27607, United States.
Helen NguyenNorth Carolina State University, Department of Biological Sciences, Raleigh, North Carolina 27607, United States.
David M ReifNorth Carolina State University, Department of Biological Sciences, Raleigh, North Carolina 27607, United States.
Erin S BakerNorth Carolina State University, Department of Chemistry, Raleigh, North Carolina 27607, United States.ORCID 0000-0001-5246-2213
Scott M BelcherNorth Carolina State University, Department of Biological Sciences, Raleigh, North Carolina 27607, United States.ORCID 0000-0002-1196-3705

Funding

Single cell, multi-parametric high throughput platform to classify endocrine disruptor potential of mixturesP42ES027704 · NIEHS · TEXAS A&M UNIVERSITY · PI Weihsueh A Chiu · 2017 to 2026
$21.2M
Translational Research Support CoreP30ES025128 · NIEHS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI Sue Fenton · 2015 to 2026
$18.3M
Uncovering the Mechanisms of PFAS-induced ImmunotoxicityP42ES031009 · NIEHS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI HOPPIN, JANE · 2020 to 2024
$9.3M
GRADUATE TRAINING IN BIOINFORMATICST32ES007329 · NIEHS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI Fred A. Wright · 2000 to 2026
$6.8M
Molecular Biotechnology Training at North Carolina State UniversityT32GM008776 · NIGMS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI KELLY, ROBERT M · 2000 to 2019
$3.9M
NC STATE MOLECULAR BIOTECHNOLOGY TRAINING PROGRAM (MBTP)T32GM133366 · NIGMS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI Jason M. Haugh, Robert M Kelly · 2020 to 2026
$3.3M
NIEHS NIH HHS P30 ES025128NIEHS NIH HHS P42 ES027704NIEHS NIH HHS P42 ES031009NIEHS NIH HHS T32 ES007329NIGMS NIH HHS T32 GM008776NIGMS NIH HHS T32 GM133366
6 · The paper itself

Abstract

As concerns over exposure to per- and polyfluoroalkyl substances (PFAS) are continually increasing, novel methods to monitor their presence and modifications are greatly needed, as some have known toxic and bioaccumulative characteristics while most have unknown effects. This task however is not simple, as the Environmental Protection Agency (EPA) CompTox PFAS list contains more than 9000 substances as of September 2020 with additional substances added continually. Nontargeted analyses are therefore crucial to investigating the presence of this immense list of possible PFAS. Here, we utilized archived and field-sampled pine needles as widely available passive samplers and a novel nontargeted, multidimensional analytical method coupling liquid chromatography, ion mobility spectrometry, and mass spectrometry (LC-IMS-MS) to evaluate the temporal and spatial presence of numerous PFAS. Over 70 PFAS were detected in the pine needles from this study, including both traditionally monitored legacy perfluoroalkyl acids (PFAAs) and their emerging replacements such as chlorinated derivatives, ultrashort chain PFAAs, perfluoroalkyl ether acids including hexafluoropropylene oxide dimer acid (HFPO-DA, "GenX") and Nafion byproduct 2, and a cyclic perfluorooctanesulfonic acid (PFOS) analog. Results from this study provide critical insight related to PFAS transport, contamination, and reduction efforts over the past six decades.

Indexed as

Alkanesulfonic AcidsFluorocarbonsChromatography, LiquidUnited StatesUnited States Environmental Protection AgencyAlkanesulfonic AcidsFluorocarbonsBiomonitoringcontaminationfluoroethersion mobilitymass spectrometryper- and polyfluoroalkyl substancesPFAS

Identifiers

PMID35175744
PMCPMC9199521

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.