Evidence map›Paper›PMID 35175731›Full record

ArticleACS infectious diseases2022

Self-Assembly of Antimicrobial Peptoids Impacts Their Biological Effects on

Josefine Eilsø Nielsen, Morgan Ashley Alford, Deborah Bow Yue Yung, Natalia Molchanova, John A Fortkort, Jennifer S Lin, Gill Diamond, Robert E W Hancock, Håvard Jenssen, Daniel Pletzer and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in ACS infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 1 pooled it
10.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 1 synthesis or guideline pooled it, 84 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
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  13. Article
  14. Antiparasitic effect of peptoids againstMicrobiology (Reading, England) · 2025
    Article
  15. Article
  16. Review
  17. Structural Optimization of Antifungal Peptoids targetingACS medicinal chemistry letters · 2025
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 5 countries.

Josefine Eilsø NielsenDepartment of Bioengineering, School of Medicine, Stanford University, Stanford, California 94305, United States.ORCID 0000-0001-9274-5533
Morgan Ashley AlfordCentre for Microbial Diseases and Immunity Research, University of British Columbia, Vancouver, British Columbia V6T 1Z4, Canada.ORCID 0000-0002-4446-817X
Deborah Bow Yue YungDepartment of Microbiology and Immunology, University of Otago, Dunedin 9054, New Zealand.
Natalia MolchanovaThe Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, California 94720, United States.
John A FortkortDepartment of Bioengineering, School of Medicine, Stanford University, Stanford, California 94305, United States.
Jennifer S LinDepartment of Bioengineering, School of Medicine, Stanford University, Stanford, California 94305, United States.ORCID 0000-0001-9169-7410
Gill DiamondDepartment of Oral Immunology and Infectious Diseases, University of Louisville, School of Dentistry, Louisville, Kentucky 40202, United States.
Robert E W HancockCentre for Microbial Diseases and Immunity Research, University of British Columbia, Vancouver, British Columbia V6T 1Z4, Canada.ORCID 0000-0001-5989-8503
Håvard JenssenDepartment of Science and Environment, Roskilde University, Roskilde 4000, Denmark.ORCID 0000-0003-0007-0335
Daniel PletzerCentre for Microbial Diseases and Immunity Research, University of British Columbia, Vancouver, British Columbia V6T 1Z4, Canada.ORCID 0000-0001-5750-7505
Reidar LundDepartment of Chemistry, University of Oslo, Oslo 0315, Norway.ORCID 0000-0001-8017-6396
Annelise E BarronDepartment of Bioengineering, School of Medicine, Stanford University, Stanford, California 94305, United States.ORCID 0000-0002-0735-6873
Stanford University · USUniversity of British Columbia · CAUniversity of Oslo · NOLawrence Berkeley National Laboratory · USRoskilde University · DKUniversity of Louisville · USUniversity of Otago · NZ

Funding

User Training and OutreachP30GM124169 · NIGMS · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI CORIE Y RALSTON · 2017 to 2026
$28.6M
Role of Innate Immune Dysregulation in the Etiology of DementiaDP1AG072438 · NIA · STANFORD UNIVERSITY · PI BARRON, ANNELISE EMILY · 2020 to 2024
$5.2M
Ampetoids as Biostable Functional Mimics of Antimicrobial PeptidesR01AI072666 · NIAID · STANFORD UNIVERSITY · PI BARRON, ANNELISE EMILY · 2007 to 2011
$1.8M
A Pixel Array Detector System for Small Angle X-ray ScatteringS10OD018483 · OD · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI CLASSEN, SCOTT · 2014 to 2014
$998k
Synthetic Antimicrobial Peptoids for Treatment of Chronic Suppurative Otitis MediaR41DC020077 · NIDCD · MAXWELL BIOSCIENCES, INC. · PI BARRON, ANNELISE EMILY, KIRSHENBAUM, KENT W · 2021 to 2021
$257k
CIHR FDN-154287NIAID NIH HHS R01 AI072666NIA NIH HHS DP1 AG072438NIDCD NIH HHS R41 DC020077NIGMS NIH HHS P30 GM124169NIH HHS S10 OD018483
6 · The paper itself

Abstract

Antimicrobial peptides (AMPs) are promising pharmaceutical candidates for the prevention and treatment of infections caused by multidrug-resistant

Indexed as

Anti-Infective AgentsPeptoidsAnti-Bacterial AgentsAntimicrobial Cationic PeptidesBacteriaAnti-Bacterial AgentsAnti-Infective AgentsAntimicrobial Cationic PeptidesPeptoidsabscessantibacterialbiofilminfectionmicellespeptoids

Identifiers

PMID35175731
PMCPMC8962514
OpenAlexW4213249709

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.