Evidence map›Paper›PMID 35175664›Full record

ArticleClinical transplantation2022

Center variations in patient selection for simultaneous heart-kidney transplantation.

Brian I Shaw, Marya L Samoylova, Andrew S Barbas, Xingxing S Cheng, Yee Lu, Lisa M McElroy, Scott Sanoff

Abstract read
In one paragraph

Article in Clinical transplantation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Bridge to simultaneous heart-kidney transplantation via extracorporeal life support: National outcomes in the new heart allocation policy era.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2025
    Article
  2. Article
  3. Heart retransplant recipients with renal dysfunction benefit from simultaneous heart-kidney transplantation.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2023
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Brian I ShawDepartment of Surgery, Duke, University, Durham, North Carolina, USA.ORCID 0000-0002-2317-6549
Marya L SamoylovaDepartment of Surgery, Duke, University, Durham, North Carolina, USA.
Andrew S BarbasDepartment of Surgery, Duke, University, Durham, North Carolina, USA.ORCID 0000-0003-3476-2313
Xingxing S ChengDepartment of Medicine, Division of Nephrology, Stanford University, Palo Alto, California, USA.
Yee LuDepartment of Medicine, Division of Nephrology, University of Michigan, Ann Arbor, Michigan, USA.
Lisa M McElroyDepartment of Surgery, Duke, University, Durham, North Carolina, USA.ORCID 0000-0003-2366-2579
Scott SanoffDepartment of Medicine, Division of Nephrology, Duke University, Durham, North Carolina, USA.

Funding

Research Project 3U54MD012530 · NIMHD · DUKE UNIVERSITY · PI JOHNSON, KIMBERLY S. · 2017 to 2022
$8.8M
Stimulating Access to Research in Residency (StARR) - NIAIDR38AI140297 · NIAID · DUKE UNIVERSITY · PI Rachel G Greenberg, David H. Harpole · 2018 to 2026
$2.4M
NIAID NIH HHS R38 AI140297NIMHD NIH HHS U54 MD012530
6 · The paper itself

Abstract

There are no established regulations governing patient selection for simultaneous heart-kidney (SHK) transplantation, creating the potential for significant center-level variations in clinical practice.

methodsUsing the United Network for Organ Sharing (UNOS) Standard Transplant Analysis and Research (STAR) file, we examined practice trends and variations in patient selection for SHK at the center level between January 1, 2004 and March 31, 2019.

resultsOverall, SHK is becoming more common with most centers performing heart transplants also performing SHK. Among patients who underwent heart transplant who were receiving dialysis, the rate of SHK varied from 22% to 86% at the center level. Among patients not on dialysis, the median estimated glomerular filtration rate (eGFR) of patients receiving SHK varied between 19 and 59 mL/min/1.73 m

conclusionVariation in SHK at the center level suggests the need for national guidelines around the selection of patients for SHK.

Indexed as

Heart TransplantationKidney TransplantationGlomerular Filtration RateHumansKidneyPatient Selectionmulti-organ transplantorgan allocationUnited Network for Organ Sharingwaitlist management

Identifiers

PMID35175664
PMCPMC10067274

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.