Evidence map›Paper›PMID 35175645›Full record

ArticleAllergy2022

Mast cell-pain connection in eosinophilic esophagitis.

Simin Zhang, Tetsuo Shoda, Seema S Aceves, Nicoleta C Arva, Mirna Chehade, Margaret H Collins, Evan S Dellon, Gary W Falk, Nirmala Gonsalves, Sandeep K Gupta and 10 more

Abstract readLetter
In one paragraph

Article in Allergy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Review
  2. Article
  3. Roles of systemic CD4Research square · 2026
    Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. The oesophagus as an immune organ.Nature reviews. Gastroenterology & hepatology · 2025
    Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Development and dysfunction of structural cells in eosinophilic esophagitis.The Journal of allergy and clinical immunology · 2024
    Review
  19. Role of Mast Cells in Eosinophilic Gastrointestinal Diseases.Immunology and allergy clinics of North America · 2024
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Simin ZhangDivision of Allergy and Immunology, University of Cincinnati College of Medicine and Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Tetsuo ShodaDivision of Allergy and Immunology, University of Cincinnati College of Medicine and Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Seema S AcevesDivision of Allergy Immunology, Departments of Pediatrics and Medicine, University of California, San Diego, California, USA.
Nicoleta C ArvaDepartment of Pathology, Feinberg School of Medicine, Ann & Robert H. Lurie Children's Hospital of Chicago, Northwestern University, Chicago, Illinois, USA.
Mirna ChehadeMount Sinai Center for Eosinophilic Disorders, Icahn School of Medicine at Mount Sinai, New York, New York, USA.ORCID 0000-0002-7177-2791
Margaret H CollinsDivision of Pathology and Laboratory Medicine, University of Cincinnati College of Medicine and Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Evan S DellonDivision of Gastroenterology and Hepatology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA.
Gary W FalkDivision of Gastroenterology, Hospital of the University of Pennsylvania, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Nirmala GonsalvesDivision of Gastroenterology & Hepatology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Sandeep K GuptaDivision of Pediatric Gastroenterology, Hepatology and Nutrition, Riley Hospital for Children/Indiana University School of Medicine, and Community Health Network, Indianapolis, Indiana, USA.
Ikuo HiranoDivision of Gastroenterology & Hepatology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Paneez KhouryNational Institute of Allergy and Infectious Diseases, NIH, Bethesda, Maryland, USA.
John LeungDivision of Gastroenterology, Tufts Medical Center, Boston, Massachusetts, USA.
Amanda K Rudman SpergelNational Institute of Allergy and Infectious Diseases, NIH, Bethesda, Maryland, USA.
Jonathan M SpergelDivision of Allergy and Immunology, University of Pennsylvania Perelman School of Medicine/Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Joshua B WechslerDivision of Gastroenterology, Hepatology & Nutrition, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, USA.ORCID 0000-0002-1275-3275
Guang-Yu YangDepartment of Pathology, Northwestern University, Chicago, Illinois, USA.
Glenn T FurutaSection of Pediatric Gastroenterology, Hepatology and Nutrition, Digestive Health Institute, Children's Hospital Colorado, University of Colorado School of Medicine, Aurora, Colorado, USA.
Marc E RothenbergDivision of Allergy and Immunology, University of Cincinnati College of Medicine and Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.ORCID 0000-0001-9790-6332
Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR) Investigators Group

Funding

The Impact of COVID-19 on People Living with Rare Diseases and Their FamiliesU2CTR002818 · NCATS · CINCINNATI CHILDRENS HOSP MED CTR · PI MICHAEL SEID · 2019 to 2026
$51.2M
Stem Cell/Organoid and Genome Editing CoreP30DK078392 · NIDDK · CINCINNATI CHILDRENS HOSP MED CTR · PI Alexander Miethke · 2007 to 2026
$24.4M
Eosinophils and Eosinophil Activation in the Pathogenesis of Human DiseaseZIAAI001130 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI KLION, AMY · 2010 to 2025
$22.5M
TRAINING (CAREER DEVELOPMENT) COMPONENTU54AI117804 · NIAID · CINCINNATI CHILDRENS HOSP MED CTR · PI Nirmala P Gonsalves · 2014 to 2026
$18.5M
Combinatory Effects of Genetic Variants in Eosinophilic EsophagitisR00AI158660 · NIAID · CINCINNATI CHILDRENS HOSP MED CTR · PI SHODA, TETSUO · 2023 to 2024
$498k
Combinatory Effects of Genetic Variants in Eosinophilic EsophagitisK99AI158660 · NIAID · CINCINNATI CHILDRENS HOSP MED CTR · PI SHODA, TETSUO · 2021 to 2022
$261k
NCATS NIH HHS U2C TR002818NIAID NIH HHS K99 AI158660NIAID NIH HHS R00 AI158660NIAID NIH HHS U54 AI117804NIDDK NIH HHS P30 DK078392
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

EnteritisEosinophilic EsophagitisEosinophiliaGastritisHumansMast CellsPain

Identifiers

PMID35175645
PMCPMC9167217

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.