Evidence map›Paper›PMID 35175587›Full record

ReviewDrugs2022

Pharmacologic Management of Persistent Pain in Cancer Survivors.

Paul Glare, Karin Aubrey, Amitabh Gulati, Yi Ching Lee, Natalie Moryl, Sarah Overton

Open access · hybridAbstract readReview
In one paragraph

Review in Drugs, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 3 pooled it
12.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 3 syntheses or guidelines pooled it, 54 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Cancer pain.Nature reviews. Disease primers · 2026
    Review
  5. Factors associated with cancer-related pain among Utah cancer survivors.Journal of cancer survivorship : research and practice · 2026
    Article
  6. Article
  7. Financial hardship and pain among cancer survivors: a French nationwide cross-sectional analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. Review
  18. Article
  19. Cancer-related pain in long-term survivors of oncological diseases: results of a survey on the current care situation.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Paul GlarePain Management Research Institute, Kolling Institute, University of Sydney and Northern Sydney Local Health District, Sydney, NSW, Australia. paul.glare@sydney.edu.au.ORCID http://orcid.org/0000-0001-6850-7025
Karin AubreyPain Management Research Institute, Kolling Institute, University of Sydney and Northern Sydney Local Health District, Sydney, NSW, Australia.
Amitabh GulatiMemorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.
Yi Ching LeeFaculty of Medicine and Health, University of Sydney, Sydney, NSW, Australia.
Natalie MorylMemorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.
Sarah OvertonPain Management Research Centre, Royal North Shore Hospital, Sydney, NSW, Australia.
The University of Sydney · AUMemorial Sloan Kettering Cancer Center · USRoyal North Shore Hospital · AU

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Improvements in screening, diagnosis and treatment of cancer has seen cancer mortality substantially diminish in the past three decades. It is estimated there are almost 20 million cancer survivors in the USA alone, but some 40% live with chronic pain after completing treatment. While a broad definition of survivorship that includes all people living with, through and beyond a cancer diagnosis-including those with active cancer-is often used, this narrative review primarily focuses on the management of pain in people who are disease-free after completing primary cancer treatment as adults. Chronic pain in this population needs a different approach to that used for people with a limited prognosis. After describing the common chronic pain syndromes caused by cancer treatment, and the pathophysiologic mechanisms involved, the pharmacologic management of entities such as post-surgical pain, chemotherapy-induced neuropathy, aromatase inhibitor musculoskeletal syndrome and checkpoint inhibitor-related pain are described. The challenges  associated with opioid prescribing in this population are given special attention. Expert guidelines on pain management in cancer survivors now recommend a combination of pharmacologic and non-pharmacologic modalities, and these are also briefly covered.

Indexed as

Cancer SurvivorsChronic PainNeoplasmsAdultAnalgesics, OpioidHumansPain ManagementPractice Patterns, Physicians'Analgesics, Opioid

Identifiers

PMID35175587
PMCPMC8888381
OpenAlexW4213168520

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.