Evidence map›Paper›PMID 35175488›Full record

ArticleBulletin of experimental biology and medicine2022

Anti-Inflammatory and Anti-Oxidant Activity of Ultra-Short Wave Diathermy on LPS-Induced Rat Lung Injury.

Q Wu, M Qu, P Zhong, Y Zeng, J Wang, Q Zhang, Ting Wang, D Liu, L Yang, J Zhou and 1 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bulletin of experimental biology and medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Q WuThe First Affiliated Hospital with Nanjing Medical University, Nanjing, Jiangsu, China.
M QuThe First Affiliated Hospital of University of South China, Department of Rehabilitation, Hengyang Medical School, University of South China, Hengyang, Hunan, China.
P ZhongThe First Affiliated Hospital of University of South China, Department of Rehabilitation, Hengyang Medical School, University of South China, Hengyang, Hunan, China.
Y ZengThe First Affiliated Hospital of University of South China, Department of Rehabilitation, Hengyang Medical School, University of South China, Hengyang, Hunan, China.
J WangThe First Affiliated Hospital of University of South China, Department of Rehabilitation, Hengyang Medical School, University of South China, Hengyang, Hunan, China.
Q ZhangThe First Affiliated Hospital of University of South China, Department of Rehabilitation, Hengyang Medical School, University of South China, Hengyang, Hunan, China.
Ting WangThe First Affiliated Hospital of University of South China, Department of Rehabilitation, Hengyang Medical School, University of South China, Hengyang, Hunan, China.
D LiuThe First Affiliated Hospital of University of South China, Department of Rehabilitation, Hengyang Medical School, University of South China, Hengyang, Hunan, China.
L YangThe First Affiliated Hospital of University of South China, Department of Rehabilitation, Hengyang Medical School, University of South China, Hengyang, Hunan, China.
J ZhouThe First Affiliated Hospital of University of South China, Department of Rehabilitation, Hengyang Medical School, University of South China, Hengyang, Hunan, China.
Tong WangThe First Affiliated Hospital with Nanjing Medical University, Nanjing, Jiangsu, China. wangtong60621@163.com.
First Affiliated Hospital of University of South China · CNUniversity of South China · CNNanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We studied the lung-protective effect and mechanisms of the anti-inflammatory and antioxidant effects of ultra-short-wave diathermy (USWD) in a rat model of LPS-induced acute lung injury. Histological examination of the lung tissues was performed and the levels of oxidative stress-related factors and inflammatory cytokines were measured. It was shown that the lung injury score, the lung wet-to-dry weight ratio (W/D), oxidative stress-related factors malondialdehyde and acyl-CoA synthetase long-chain family member 4 (ACSL4), and inflammatory cytokines were increased after LPS administration, while USWD treatment reduced these parameters. In addition, superoxide dismutase and glutathione peroxidase 4 were decreased in rats with LPS-induced acute lung injury, while USWD therapy up-regulated the expression of these enzymes. Thus, USWD could antagonize lung injury by inhibiting oxidative stress and inflammatory response in rats with acute lung injury. USWD can be a promising adjunctive treatment to counter oxidative stress and inflammation and a potential therapeutic candidate for the treatment of patients with this pathology.

Indexed as

Acute Lung InjuryDiathermyAnimalsAnti-Inflammatory AgentsAntioxidantsHumansLipopolysaccharidesLungOxidative StressRadio WavesRatsAnti-Inflammatory AgentsAntioxidantsLipopolysaccharidesacute lung injuryinflammationoxidative stressultra-short wave diathermy therapy

Identifiers

PMID35175488
PMCPMC8853088
OpenAlexW4221054004

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.