Evidence map›Paper›PMID 35174738›Full record

ArticleDrug delivery2022

Olive oil and clove oil-based nanoemulsion for topical delivery of terbinafine hydrochloride:

Uzma Gul, Muhammad Imran Khan, Asadullah Madni, Muhammad Farhan Sohail, Mubashar Rehman, Akhtar Rasul, Leena Peltonen

Open access · goldAbstract read
In one paragraph

Article in Drug delivery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 70 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Uzma GulRiphah Institute of Pharmaceutical Sciences (RIPS), Riphah International University, Lahore, Pakistan.
Muhammad Imran KhanRiphah Institute of Pharmaceutical Sciences (RIPS), Riphah International University, Lahore, Pakistan.
Asadullah MadniDepartment of Pharmaceutics, Faculty of Pharmacy, The Islamia University of Bahawalpur, Bahawalpur, Pakistan.
Muhammad Farhan SohailRiphah Institute of Pharmaceutical Sciences (RIPS), Riphah International University, Lahore, Pakistan.
Mubashar RehmanDepartment of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
Akhtar RasulDepartment of Pharmaceutics, Faculty of Pharmaceutical Sciences, Government College University, Faisalabad, Pakistan.ORCID 0000-0002-9321-0087
Leena PeltonenDrug Research Program, Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland.ORCID 0000-0002-6651-2792
Riphah International University · PKGovernment College University, Faisalabad · PKIslamia University of Bahawalpur · PKQuaid-i-Azam University · PKUniversity of Helsinki · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this article, formulation studies for terbinafine hydrochloride nanoemulsions, prepared by high-energy ultrasonication technique, are described. Pseudo-ternary phase diagram was constructed in order to find out the optimal ratios of oil and surfactant/co-solvent mixture for nanoemulsion production. Clove and olive oils were selected as oil phase. Based on the droplet size evaluation, maximum nanoemulsion region were determined for formulation development. Further characterization included polydispersity index (PDI), zeta potential, Fourier transform infrared (FT-IR) spectroscopy, morphology, pH, viscosity, refractive index,

Indexed as

Administration, TopicalAnimalsAntifungal AgentsChemistry, PharmaceuticalClove OilDrug CarriersEmulsionsHydrogen-Ion ConcentrationMiceNanoparticlesOlive OilParticle SizeSkin AbsorptionSolubilitySurface PropertiesTerbinafineAntifungal AgentsClove OilDrug CarriersEmulsionsOlive OilTerbinafineNanoemulsionpseudo-ternary phase diagramterbinafine hydrochloridetopical deliveryultrasonication

Identifiers

PMID35174738
PMCPMC8856056
OpenAlexW4213084273

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.