Evidence map›Paper›PMID 35174730›Full record

ArticleGlobal spine journal2022

Establishing the Socio-Economic Impact of Degenerative Cervical Myelopathy Is Fundamental to Improving Outcomes [AO Spine RECODE-DCM Research Priority Number 8].

Benjamin M Davies, Richard Phillips, David Clarke, Julio C Furlan, Andreas K Demetriades, Jamie Milligan, Christopher D Witiw, James S Harrop, Bizhan Aarabi, Shekar N Kurpad and 7 more

Open access · goldAbstract read
In one paragraph

Article in Global spine journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
10.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 11 institutions in 5 countries.

Benjamin M DaviesDepartment of Neurosurgery, University of Cambridge, Cambridge, United Kingdom.ORCID https://orcid.org/0000-0003-0591-5069
Richard PhillipsGoffin Consultancy, Canterbury, United Kingdom.
David ClarkeDepartment of Neurosurgery, University of Cambridge, Cambridge, United Kingdom.
Julio C FurlanKITE Research Institute, University Health Network, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0002-2038-0018
Andreas K DemetriadesDepartment of Clinical Neurosciences, Edinburgh, United Kingdom.
Jamie MilliganDepartment of Family Medicine, McMaster University, Hamilton, Ontario, Canada.
Christopher D WitiwDivision of Neurosurgery, Department of Surgery, University of Toronto, Toronto, Ontario, Canada.
James S HarropDepartment of Neurological Surgery, Thomas Jefferson University, Philadelphia, PA, USA.
Bizhan AarabiDepartment of Neurosurgery, University of Maryland School of Medicine, Baltimore, MD, USA.
Shekar N KurpadDepartment of Neurosurgery, Medical College of Wisconsin, Wauwatosa, WI, USA.
James D GuestDepartment of Neurosurgery and The Miami Project to Cure Paralysis, The Miller School of Medicine, University of Miami, Miami, FL, USA.
Jefferson R WilsonDivision of Neurosurgery, Department of Surgery, University of Toronto, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0001-5965-0305
Brian K KwonDepartment of Orthopedics, Vancouver Spine Surgery Institute, The University of British Columbia, Vancouver, British Columbia, Canada.
Alexander R VaccaroDepartment of Orthopaedic Surgery, Rothman Orthopaedic Institute, Thomas Jefferson University, Philadelphia, PA, USA.
Michael G FehlingsDivision of Neurosurgery, Department of Surgery, University of Toronto, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0002-5722-6364
Vafa Rahimi-MovagharDepartment of Neurosurgery, Sina Trauma and Surgery Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Mark R N KotterDepartment of Neurosurgery, University of Cambridge, Cambridge, United Kingdom.
University of Cambridge · GBUniversity of Toronto · CAThomas Jefferson University · USMcMaster University · CAMedical College of Wisconsin · USSina Hospital · IRUniversity Health Network · CAUniversity of British Columbia · CAUniversity of Edinburgh · GBUniversity of Maryland, Baltimore · USUniversity of Miami · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designLiterature Review (Narrative).

objectiveTo contextualize AO Spine RECODE-DCM research priority number 5: What is the socio-economic impact of DCM? (The financial impact of living with DCM to the individual, their supporters, and society as a whole).

methodsIn this review, we introduce the methodology of health-economic investigation, including potential techniques and approaches. We summarize the current health-economic evidence within DCM, so far focused on surgical treatment. We also cover the first national estimate, in partnership with Myelopathy.org from the United Kingdom, of the cost of DCM to society. We then demonstrate the significance of this question to advancing care and outcomes in the field.

resultsDCM is a common and often disabling condition, with a significant lack of recognition. While evidence demonstrates the cost-effectives of surgery, even among higher income countries, health inequalities exist. Further the prevalent residual disability in myelopathy, despite treatment affects both the individual and society as a whole. A report from the United Kingdom provides the first cost-estimate to their society; an annual cost of ∼£681.6 million per year, but this is likely a significant underestimate.

conclusionA clear quantification of the impact of DCM is needed to raise the profile of a common and disabling condition. Current evidence suggests this is likely to be globally substantial.

Indexed as

cervical myelopathycervical spondylosiscervical stenosisdegenerationdisc herniationhealth economicsossification posterior longitudinal ligamentpolicyresearch prioritiessocioeconomics

Identifiers

PMID35174730
PMCPMC8859704
OpenAlexW4213266998

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.