Evidence map›Paper›PMID 35174360›Full record

ArticleIEEE open journal of ultrasonics, ferroelectrics, and frequency control2021

Spatiotemporal Bayesian Regularization for Cardiac Strain Imaging: Simulation and

Rashid Al Mukaddim, Nirvedh H Meshram, Ashley M Weichmann, Carol C Mitchell, Tomy Varghese

Abstract read
In one paragraph

Article in IEEE open journal of ultrasonics, ferroelectrics, and frequency control, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Lagrangian deformation tracking for strain imaging.Progress in biomedical engineering (Bristol, England) · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rashid Al MukaddimDepartment of Medical Physics, University of Wisconsin School of Medicine and Public Health, Madison, WI 53706 USA.ORCID 0000-0001-7042-7163
Nirvedh H MeshramDepartment of Medical Physics, University of Wisconsin School of Medicine and Public Health, Madison, WI 53706 USA.ORCID 0000-0003-4005-9798
Ashley M WeichmannSmall Animal Imaging and Radiotherapy Facility, UW Carbone Cancer Center, Madison, WI 53705 USA.
Carol C MitchellDepartment of Medicine/Division of Cardiovascular Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792 USA.ORCID 0000-0001-6445-3306
Tomy VargheseDepartment of Medical Physics, University of Wisconsin School of Medicine and Public Health, Madison, WI 53706 USA.ORCID 0000-0003-3299-9130

Funding

UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Christian Capitini · 1985 to 2026
$142.6M
Early Detection of Vascular Dysfunction Using Biomarkers from Lagrangian Carotid Strain ImagingR01HL147866 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI VARGHESE, TOMY · 2020 to 2023
$2.9M
Real-time Ultrasonic Monitoring of Tumor AblationR01CA112192 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI VARGHESE, TOMY · 2007 to 2017
$2.6M
Ultrasonic and Photoacoustic Imaging System for Cancer & Cardiovascular ResearchS10OD018505 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI VARGHESE, TOMY · 2015 to 2015
$908k
NCI NIH HHS P30 CA014520NCI NIH HHS R01 CA112192NHLBI NIH HHS R01 HL147866NIH HHS S10 OD018505
6 · The paper itself

Abstract

Cardiac strain imaging (CSI) plays a critical role in the detection of myocardial motion abnormalities. Displacement estimation is an important processing step to ensure the accuracy and precision of derived strain tensors. In this paper, we propose and implement Spatiotemporal Bayesian regularization (STBR) algorithms for two-dimensional (2-D) normalized cross-correlation (NCC) based multi-level block matching along with incorporation into a Lagrangian cardiac strain estimation framework. Assuming smooth temporal variation over a short span of time, the proposed STBR algorithm performs displacement estimation using at least four consecutive ultrasound radio-frequency (RF) frames by iteratively regularizing 2-D NCC matrices using information from a local spatiotemporal neighborhood in a Bayesian sense. Two STBR schemes are proposed to construct Bayesian likelihood functions termed as Spatial then Temporal Bayesian (STBR-1) and simultaneous Spatiotemporal Bayesian (STBR-2). Radial and longitudinal strain estimated from a finite-element-analysis (FEA) model of realistic canine myocardial deformation were utilized to quantify strain bias, normalized strain error and total temporal relative error (TTR). Statistical analysis with one-way analysis of variance (ANOVA) showed that all Bayesian regularization methods significantly outperform NCC with lower bias and errors (

Indexed as

Bayesian regularizationCardiac strain imagingcardiac ultrasoundhigh frequency ultrasoundmulti-level block matchingmurine echocardiographyspatiotemporal information

Identifiers

PMID35174360
PMCPMC8846604

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.