ReviewPsychiatric research and clinical practice2021
Minds and Brains, Sleep and Psychiatry.
Review in Psychiatric research and clinical practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 28 citations in OpenAlex.
- Sleep and Mental Health: Unveiling the Critical Role of Sleep in Brain Function and Psychiatric Disorders.Biological psychiatry · 2025Article
- Adaptive consolidation of active inference: excitatory and inhibitory mechanisms for organizing feedforward and feedback memory systems in sleep.Cerebral cortex (New York, N.Y. : 1991) · 2025Review
- CB-1 receptor agonist drastically changes oscillatory activity, defining active sleep.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- The futuristic manifolds of REM sleep.Journal of sleep research · 2025Review
- The power of the group: How neuroscience supports expanding the therapeutic dyad through group psychotherapy.Frontiers in psychology · 2025Article
- Integrating neuropsychoanalytic and neuropsychiatric perspectives into psychiatric clinical neuroscience curricula: a conceptual overview.Frontiers in medicine · 2025Review
- A parahippocampal-sensory Bayesian vicious circle generates pain or tinnitus: a source-localized EEG study.Brain communications · 2023Article
- Neurophysiological mechanisms of implicit and explicit memory in the process of consciousness.Journal of neurophysiology · 2022Review
- The Active Inference Model of Coherence Therapy.Frontiers in human neuroscience · 2022Article
- Non-Constructive Ruminations, Insomnia and Nightmares: Trio of Vulnerabilities to Suicide Risk.Nature and science of sleep · 2022Article
- Balancing Prediction and Surprise: A Role for Active Sleep at the Dawn of Consciousness?Frontiers in systems neuroscience · 2021Article
Corrections and comments
- Erratum issued
Authors and funding
3 authors at 1 institution in 3 countries.
Funding
Abstract
objectiveThis article offers a philosophical thesis for psychiatric disorders that rests upon some simple truths about the mind and brain. Specifically, it asks whether the
methodsOur starting point is that the mind and brain are emergent aspects of the same (neuronal) dynamics; namely, the brain-mind. Our endpoint is that synaptic dysconnection syndromes inherit the same dual aspect; namely, aberrant inference or belief updating on the one hand, and a failure of neuromodulatory synaptic gain control on the other. We start with some basic considerations from sleep research that integrate the phenomenology of dreaming with the neurophysiology of sleep.
resultsWe then leverage this treatment by treating the brain as an organ of inference. Our particular focus is on the role of precision (i.e., the representation of uncertainty) in belief updating and the accompanying synaptic mechanisms.
conclusionsFinally, we suggest a dual aspect approach-based upon belief updating (i.e., mind processes) and its neurophysiological implementation (i.e., brain processes)-has a wide explanatory compass for psychiatry and various movement disorders. This approach identifies the kind of pathophysiology that underwrites psychopathology-and points to certain psychotherapeutic and psychopharmacological targets, which may stand in mechanistic relation to each other.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.