ArticleFrontiers in molecular biosciences2021
Long-Term Effects of Aircraft Noise Exposure on Vascular Oxidative Stress, Endothelial Function and Blood Pressure: No Evidence for Adaptation or Tolerance Development.
Article in Frontiers in molecular biosciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 28 citations in OpenAlex.
- Risk Factors for Cardiovascular Disease: Epidemiology, Screening, Prevention, and Therapeutic Interventions.MedComm · 2026Review
- Angiotensin-Converting Enzyme (ACE) Inhibitors and Statins Mitigate Negative Cardiovascular and Pulmonary Effects of Particulate Matter in a Mouse Exposure Model.Antioxidants (Basel, Switzerland) · 2026Article
- A comprehensive review/expert statement on environmental risk factors of cardiovascular disease.Cardiovascular research · 2025Review
- Effects of Mobile Electromagnetic Exposure on Brain Oscillations and Cortical Excitability: Scoping Review.Sensors (Basel, Switzerland) · 2025Article
- Community impacts of aviation noise: a pilot survey.Journal of exposure science & environmental epidemiology · 2025Article
- Noise causes cardiovascular disease: it's time to act.Journal of exposure science & environmental epidemiology · 2025Review
- Vasomotion loss precedes impaired cerebrovascular reactivity and microbleeds in cerebral amyloid angiopathy.Brain communications · 2025Article
- Association of transportation noise with cardiovascular diseases.Clinical cardiology · 2024Review
- Environmental Impacts on Cardiovascular Health and Biology: An Overview.Circulation research · 2024Review
- Health position paper and redox perspectives - Disease burden by transportation noise.Redox biology · 2024Review
- Vascular Redox Signaling, Endothelial Nitric Oxide Synthase Uncoupling, and Endothelial Dysfunction in the Setting of Transportation Noise Exposure or Chronic Treatment with Organic Nitrates.Antioxidants & redox signaling · 2023Review
- Noise, Air, and Heavy Metal Pollution as Risk Factors for Endothelial Dysfunction.European cardiology · 2023Review
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- An Oxidative Stress Biomarker for Noise-Associated Stroke: Evidence from Human and Mice.Noise & healthArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
24 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Transportation noise is recognized as an important cardiovascular risk factor. Key mechanisms are noise-triggered vascular inflammation and oxidative stress with subsequent endothelial dysfunction. Here, we test for adaptation or tolerance mechanisms in mice in response to chronic noise exposure. C57BL/6J mice were exposed to aircraft noise for 0, 4, 7, 14 and 28d at a mean sound pressure level of 72 dB(A) and peak levels of 85 dB(A). Chronic aircraft noise exposure up to 28d caused persistent endothelial dysfunction and elevation of blood pressure. Likewise, reactive oxygen species (ROS) formation as determined by dihydroethidium (DHE) staining and HPLC-based measurement of superoxide formation in the aorta/heart/brain was time-dependently increased by noise. Oxidative burst in the whole blood showed a maximum at 4d or 7d of noise exposure. Increased superoxide formation in the brain was mirrored by a downregulation of neuronal nitric oxide synthase (
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Registered trials
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