Evidence map›Paper›PMID 35173924›Full record

ArticleBasic and clinical neuroscience

Guillain-Barre Syndrome and COVID-19 Vaccine: A Report of Nine Patients.

Narges Karimi, Reza Boostani, Farzad Fatehi, Akram Panahi, Ali Asghar Okhovat, Bentolhoda Ziaadini, Keivan Basiri, Siamak Abdi, Farnaz Sinaei, Mojtaba Rezaei and 3 more

Open access · diamondAbstract read
In one paragraph

Article in Basic and clinical neuroscience. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
3.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.

  1. Pooled it
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  12. Post COVID-19 vaccination Guillain-Barre syndrome: three cases.Human vaccines & immunotherapeutics · 2022
    Article
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  15. Article
  16. Cubital Tunnel Syndrome Temporally after COVID-19 Vaccination.Tropical medicine and infectious disease · 2022
    Article
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  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Narges KarimiImmunogenetics Research Center, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.ORCID https://orcid.org/0000-0001-5912-3732
Reza BoostaniDepartment of Neurology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.ORCID https://orcid.org/0000-0001-7998-9592
Farzad FatehiDepartment of Neurology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0002-6774-7825
Akram PanahiDepartment of Neurology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0003-3746-1831
Ali Asghar OkhovatDepartment of Neurology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0002-9286-4943
Bentolhoda ZiaadiniDepartment of Neurology, Kerman Neuroscience Research Center, Kerman University of Medical Science, Kerman, Iran.ORCID https://orcid.org/0000-0003-4312-6060
Keivan BasiriDepartment of Neurology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.ORCID https://orcid.org/0000-0001-8621-9625
Siamak AbdiDepartment of Neurology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0002-1339-346X
Farnaz SinaeiDepartment of Neurology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0002-7332-7317
Mojtaba RezaeiDepartment of Neurology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0001-7855-7659
Gholamreza ShamsaeiNeurology Department, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.ORCID https://orcid.org/0000-0001-9596-9882
Behnaz AnsariDepartment of Neurology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.ORCID https://orcid.org/0000-0003-0368-5888
Shahriar NafissiDepartment of Neurology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0003-4763-4310
Tehran University of Medical Sciences · IRIsfahan University of Medical Sciences · IRShariati Hospital · IRAhvaz Jundishapur University of Medical Sciences · IRMashhad University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionGuillain-Barre Syndrome (GBS) is an autoimmune acute inflammatory demyelinating polyneuropathy usually elicited by an upper respiratory tract infection. Several studies reported GBS associated with Coronavirus Disease 2019 (COVID-19) infection. In this study, we described nine GBS patients following the COVID-19 vaccine.

methodsIn this study, nine patients were introduced from six referral centers for neuromuscular disorders in Iran between April 8 and June 20, 2021. Four patients received the Sputnik V, three patients received the Sinopharm, and two cases received the AstraZeneca vaccine. All patients were diagnosed with GBS evidenced by nerve conduction studies and/or cerebrospinal fluid analysis.

resultsThe median age of the patients was 54.22 years (ranged 26-87 years), and seven patients were male. The patients were treated with Intravenous Immunoglobulin (IVIg) or Plasma Exchange (PLEX). All patients were discharged with some improvements.

conclusionThe link between the COVID-19 vaccine and GBS is not well understood. Given the prevalence of GBS over the population, this association may be coincidental; therefore, more studies are needed to investigate a causal relationship.

Indexed as

AstraZenecaCoronavirus-2019Guillain-Barre syndromeSinopharmSputnikVaccine

Identifiers

PMID35173924
PMCPMC8818119
OpenAlexW3209188723

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.