ArticleBasic and clinical neuroscience
The Role of Oxidant-Antioxidant Status in Suicide Behavior in Kurdish Ethnicity.
Article in Basic and clinical neuroscience. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.
- Inflammation and nitro-oxidative stress in current suicidal attempts and current suicidal ideation: a systematic review and meta-analysis.Molecular psychiatry · 2022Pooled it
- Oxidative Stress in Depression: A Case-control Study of Serum MDA Levels and Lipid Levels in Patients With Depression in a Tertiary Care Hospital in South India.Indian journal of psychological medicine · 2024Article
- Evaluation of neutrophile-to-lymphocyte ratio and lipid profile in non-violent suicide attempters: a mechanistic study.Journal of injury & violence research · 2024Article
- Possible effect of exercise with anti-fatigue nutrition on ROS-induced depression and suicide risk: a review.Physical activity and nutrition · 2024Article
- Oxidative stress parameters in women and men with suicidal thoughts and following a suicide attempt.Frontiers in psychiatry · 2024Article
- Association of Serum Vitamin D Levels with the Risk of Suicidal Behavior in Ilam, Iran: A Brief Report.Iranian journal of medical sciences · 2023Article
- GFAP and Neuron Specific Enolase (NSE) in the Serum of Suicide Attempters.Medical journal of the Islamic Republic of Iran · 2022Article
- Suicide capability within the ideation-to-action framework: A systematic scoping review.PloS one · 2022Article
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionOxidative stress plays a critical role in the pathogenesis of neurodegenerative and neuropsychiatric disorders. However, its role in suicidal behavior has not been clarified yet. Consequently, we aimed to evaluate the oxidant-antioxidant status in the serum of suicide attempters in Ilam city.
methodsFifty suicide attempters and 40 control subjects (volunteers) aged 18-35 years were studied in the current experiment. To consider the oxidant-antioxidant status, serum levels of Malondialdehyde (MDA), Nitric Oxide (NO), Superoxide Dismutase (SOD), and the Total Antioxidant Capacity (TAC) were measured.
resultsSerum levels of SOD and TAC were significantly lower in the suicide attempters group compared to the controls. Furthermore, serum NO level was significantly higher in the suicide attempters compared to the control groups. Interestingly, the serum level of MDA was significantly lower in the suicide attempters compared to the control groups.
conclusionThe oxidative stress without MDA elevation, detected in suicide attempters, can be considered a biochemical hallmark in suicide behavior.
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