Evidence map›Paper›PMID 35173908›Full record

ArticleUpsala journal of medical sciences2022

Automated data extraction of electronic medical records: Validity of data mining to construct research databases for eligibility in gastroenterological clinical trials.

Nora Joseph, Ida Lindblad, Sara Zaker, Sharareh Elfversson, Maria Albinzon, Øyvind Ødegård, Li Hantler, Per M Hellström

Abstract read
In one paragraph

Article in Upsala journal of medical sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nora JosephDepartment of Medical Sciences, Gastroenterology and Hepatology, Uppsala University, Uppsala.
Ida LindbladIQVIA Sweden AB, Solna, Stockholm, Sweden.
Sara ZakerIQVIA Sweden AB, Solna, Stockholm, Sweden.
Sharareh ElfverssonIQVIA Sweden AB, Solna, Stockholm, Sweden.
Maria AlbinzonIQVIA Sweden AB, Solna, Stockholm, Sweden.
Øyvind ØdegårdIQVIA Sweden AB, Solna, Stockholm, Sweden.
Li HantlerIQVIA Sweden AB, Solna, Stockholm, Sweden.
Per M HellströmDepartment of Medical Sciences, Gastroenterology and Hepatology, Uppsala University, Uppsala.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundElectronic medical records (EMRs) are adopted for storing patient-related healthcare information. Using data mining techniques, it is possible to make use of and derive benefit from this massive amount of data effectively. We aimed to evaluate validity of data extracted by the Customized eXtraction Program (CXP).

methodsThe CXP extracts and structures data in rapid standardised processes. The CXP was programmed to extract TNFα-native active ulcerative colitis (UC) patients from EMRs using defined International Classification of Disease-10 (ICD-10) codes. Extracted data were read in parallel with manual assessment of the EMR to compare with CXP-extracted data.

resultsFrom the complete EMR set, 2,802 patients with code K51 (UC) were extracted. Then, CXP extracted 332 patients according to inclusion and exclusion criteria. Of these, 97.5% were correctly identified, resulting in a final set of 320 cases eligible for the study. When comparing CXP-extracted data against manually assessed EMRs, the recovery rate was 95.6-101.1% over the years with 96.1% weighted average sensitivity.

conclusionUtilisation of the CXP software can be considered as an effective way to extract relevant EMR data without significant errors. Hence, by extracting from EMRs, CXP accurately identifies patients and has the capacity to facilitate research studies and clinical trials by finding patients with the requested code as well as funnel down itemised individuals according to specified inclusion and exclusion criteria. Beyond this, medical procedures and laboratory data can rapidly be retrieved from the EMRs to create tailored databases of extracted material for immediate use in clinical trials.

Indexed as

Data MiningElectronic Health RecordsDatabases, FactualHumansInternational Classification of DiseasesBig datadata analyticsdata extractiondata miningelectronic medical records

Identifiers

PMID35173908
PMCPMC8809051

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.