Evidence map›Paper›PMID 35173893›Full record

ArticleJournal of clinical and experimental dentistry2022

Valdir-Gouveia Garcia, Valquíria-Simone-Degraf-Gomes Calil, Jânderson-de Medeiros Cardoso, Marcia Hinz, Tiago-Esgalha da Rocha, Edilson Ervolino, Daniela-Maria-Janjacomo Miessi, Luan-Felipe Toro, Daniela-Atili Brandini, Letícia-Helena Theodoro

Open access · diamondAbstract read
In one paragraph

Article in Journal of clinical and experimental dentistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Valdir-Gouveia GarciaLatin American Institute of Dental Research and Teaching, School of Dentistry Ilapeo, Curitiba, Paraná, Brazil.
Valquíria-Simone-Degraf-Gomes CalilLatin American Institute of Dental Research and Teaching, School of Dentistry Ilapeo, Curitiba, Paraná, Brazil.
Jânderson-de Medeiros CardosoLatin American Institute of Dental Research and Teaching, School of Dentistry Ilapeo, Curitiba, Paraná, Brazil.
Marcia HinzLatin American Institute of Dental Research and Teaching, School of Dentistry Ilapeo, Curitiba, Paraná, Brazil.
Tiago-Esgalha da RochaGroup for the Research and Study of Laser in Dentistry, São Paulo State University (UNESP), School of Dentistry, Araçatuba, São Paulo, Brazil.
Edilson ErvolinoGroup for the Research and Study of Laser in Dentistry, São Paulo State University (UNESP), School of Dentistry, Araçatuba, São Paulo, Brazil.
Daniela-Maria-Janjacomo MiessiGroup for the Research and Study of Laser in Dentistry, São Paulo State University (UNESP), School of Dentistry, Araçatuba, São Paulo, Brazil.
Luan-Felipe ToroDepartment of Basic Sciences, School of Dentistry, São Paulo State University (UNESP), Araçatuba, São Paulo, Brazil.
Daniela-Atili BrandiniDepartment of Diagnosis and Surgery, School of Dentistry, São Paulo State University (UNESP), Araçatuba, São Paulo, Brazil.
Letícia-Helena TheodoroGroup for the Research and Study of Laser in Dentistry, São Paulo State University (UNESP), School of Dentistry, Araçatuba, São Paulo, Brazil.
Universidade Estadual Paulista (Unesp) · BRLatin American Sepsis Institute · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe repair of bone defects has been the subject of many studies that have shown inconclusive results as to what is the best bone substitute. MATERIAL AND

methodsBone defects (Ø 2 mm) were induced on the tibia of seventy-two rats, which were distributed into the following four groups/treatments (n=18 each): Control: no treatment; EMD: enamel matrix derived protein; PBM: photobiomodulation therapy (660 nm, 0,035 W, 60 s); EMD + PBM: EMD and immediate treatment with PBM (660 nm, 0,035 W, 60 s). Six animals from each group were euthanized after 10, 30 and 60 days. Histological and immunohistochemistry analyses (osteocalcin - OCN and tartrate-resistant acid phosphatase - TRAP) were performed with scores for each of the biological events.

resultsAll performed treatments resulted in an increased filling and maturation of bone tissue, being greater in the EMD and EMD + PBM groups in the 30 day period, compared to the Control group. The immunostaining of OCN was greater at 60 days in all treated groups than in the Control over the same period. TRAP immunostaining was higher at 30 days in all treated groups, and lower in groups EMD and PBM after 60 days, compared to the Control over the same period. There was greater immunostaining in the EMD + PBM group after 10 days than in the Control and EMD groups in the same period.

conclusionsThese results lead to the conclusion that treatments with EMD and PBM, both separate and in association were effective in filling and maturing bone tissue in tibial bone cavities, with greater effectiveness in the period of 30 days in the EMD and EMD + PBM groups.

Identifiers

PMID35173893
PMCPMC8842292
OpenAlexW4210528849

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.