ArticleAmerican journal of translational research2022
Clinical efficacy and prognosis of standard large trauma craniotomy for patients with severe frontotemporal craniocerebral injury.
Article in American journal of translational research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Clinical Significance of Serum MMP-9, S100-β and GFAP in Patients with Mental Disorders after Traumatic Brain Injury.Actas espanolas de psiquiatria · 2025Article
- Ameliorative properties of quercetin in the treatment of traumatic brain injury: a mechanistic review based on underlying mechanisms.Molecular biology reports · 2024Review
- Status and influencing factors of disease uncertainty among family caregivers of patients with moderate and severe craniocerebral injury: a quantitative and qualitative study.Acta neurochirurgica · 2022Article
- Investigation of the Effects of Large Bone Flap Craniotomy on Cerebral Hemodynamics, Intracranial Infection Rate, and Nerve Function in Patients with Severe Craniocerebral Trauma.Contrast media & molecular imaging · 2022Article
- Treatment effects of monosialotetrahexosylganglioside on severe traumatic brain injury in adults.American journal of translational research · 2022Article
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Authors and funding
2 authors.
Funding
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Abstract
objectiveTo observe the clinical efficacy, incidence of postoperative complications, and the quality of life in patients with severe craniocerebral injury undergoing standard large trauma craniotomy.
methodsSeventy-eight patients with severe craniocerebral injury who had been admitted to Hubei Hanchuan People's Hospital were selected retrospectively and assigned into an observation group and control group according to the treatment received, with 39 patients in each group. Patients in the control group were treated with conventional decompressive craniotomy and those in the observation group with standard large trauma craniotomy. The prognosis (GOS score), intracranial pressure before and after surgery, neurological functions (NIHSS score), cerebral hemodynamics (Vm, Vs, PI), quality of life (SF-36 score) and postoperative complications were compared.
resultsThe number of patients whose GOS scores were graded 5 was markedly higher in the observation group than that in the control group (P<0.05). The postoperative intracranial pressure and NIHSS scores in the observation group were lower than those in the control group (P<0.001). The postoperative Vm, Vs and PI were lower in the observation group than those in the control group, respectively (P<0.001). There was no statistical difference in the incidence of complications in the two groups (P>0.05). The SF-36 scores in the observation group were higher than those of the control group (P<0.01).
conclusionStandard large trauma craniotomy is effective in treating patients with severe frontotemporal craniocerebral injury. It decreases intracranial pressure, improves neurological function and quality of life and results in a good prognosis.
Indexed as
Identifiers
35173867PMC8829637What OpenQuestion holds
Registered trials
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