Evidence map›Paper›PMID 35173852›Full record

ArticleAmerican journal of translational research2022

Lung-borne systemic inflammation in mechanically ventilated infant rats due to high PEEP, oxygen, and hypocapnia.

Philipp Baumann, Francesco Greco, Pietro L'Abate, Sven Wellmann, Susanne Wiegert, Vincenzo Cannizzaro

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in American journal of translational research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Philipp BaumannDepartment of Intensive Care Medicine and Neonatology, University Children's Hospital Zurich Zurich, Switzerland.
Francesco GrecoDepartment of Intensive Care Medicine and Neonatology, University Children's Hospital Zurich Zurich, Switzerland.
Pietro L'AbateDepartment of Intensive Care Medicine and Neonatology, University Children's Hospital Zurich Zurich, Switzerland.
Sven WellmannZurich Center for Integrative Human Physiology (ZIHP), University Zurich Zurich, Switzerland.
Susanne WiegertDepartment of Intensive Care Medicine and Neonatology, University Children's Hospital Zurich Zurich, Switzerland.
Vincenzo CannizzaroDepartment of Intensive Care Medicine and Neonatology, University Children's Hospital Zurich Zurich, Switzerland.
Swiss Integrative Center for Human Health · CHUniversity Children's Hospital Zurich · CHUniversity Hospital of Zurich · CHUniversity Hospital Regensburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntensive care practice calls for ventilator adjustments due to fast-changing clinical conditions in ventilated critically ill children. These adaptations include positive end-expiratory pressure (PEEP), fraction of inspired oxygen (FiO

methodsFourteen-day old Wistar rat pups were randomized to the following groups: (a) "control" with tidal volume ~8 mL/kg, PEEP 5 cmH

resultsInterleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) were driven by FiO

conclusionAlterations of PEEP, FiO

Indexed as

hyperoxiahypocapniaInterleukin-6positive end-expiratory pressuretissue plasminogen activator inhibitor type-1tumor necrosis factor-α

Identifiers

PMID35173852
PMCPMC8829610
OpenAlexW4213391874

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.