Evidence map›Paper›PMID 35173733›Full record

ArticleFrontiers in immunology2022

Inactivated Rabies Virus Vectored MERS-Coronavirus Vaccine Induces Protective Immunity in Mice, Camels, and Alpacas.

Hang Chi, Yanqun Wang, Entao Li, Xiwen Wang, Hualei Wang, Hongli Jin, Qiuxue Han, Zhenshan Wang, Xinyue Wang, Airu Zhu and 12 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Epidemiology of rabies in camels.Journal of advanced veterinary and animal research · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

22 authors at 6 institutions in 1 country.

Hang ChiChangchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun, China.
Yanqun WangState Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Entao LiChangchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun, China.
Xiwen WangFood and Drug Inspection Laboratory, Administration for Drug and Instrument Supervision and Inspection, Beijing, China.
Hualei WangKey Laboratory of Zoonosis Research, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, China.
Hongli JinKey Laboratory of Zoonosis Research, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, China.
Qiuxue HanChangchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun, China.
Zhenshan WangChangchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun, China.
Xinyue WangChangchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun, China.
Airu ZhuState Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Jing SunState Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Zhen ZhuangState Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Lu ZhangHealth and Quarantine Laboratory, Guangzhou Customs Technology Center, Guangzhou, China.
Jingmeiqi YeInstitute of Education, Tsinghua University, Beijing, China.
Haijun WangJilin Wild Animal Rescue Breeding Center Committee, Jilin Province Northeast Tiger Garden, Changchun, China.
Na FengChangchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun, China.
Mingda HuSate Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Biotechnology, Beijing, China.
Yuwei GaoChangchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun, China.
Jincun ZhaoState Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Yongkun ZhaoChangchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun, China.
Songtao YangChangchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun, China.
Xianzhu XiaChangchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun, China.
Chinese Academy of Agricultural Sciences · CNJilin University · CNState Key Laboratory of Respiratory Disease · CNGuangzhou Medical University · CNGuangdong Inspection and Quarantine Technology Center (China) · CNTsinghua University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Middle East respiratory syndrome coronavirus (MERS-CoV) is an emergent coronavirus that has caused frequent zoonotic events through camel-to-human spillover. An effective camelid vaccination strategy is probably the best way to reduce human exposure risk. Here, we constructed and evaluated an inactivated rabies virus-vectored MERS-CoV vaccine in mice, camels, and alpacas. Potent antigen-specific antibody and CD8

Indexed as

AnimalsAntibodies, NeutralizingAntibodies, ViralCamelids, New WorldCamelusCD8-Positive T-LymphocytesCell Line, TumorChlorocebus aethiopsCoronavirus InfectionsCricetinaeFemaleGenetic VectorsMaleMiceMice, Inbred C57BLMiddle East Respiratory Syndrome CoronavirusAntibodies, NeutralizingAntibodies, ViralVaccines, SyntheticViral VaccinesalpacacamelMERS-CoVmicerabies virus vectorvaccine

Identifiers

PMID35173733
PMCPMC8842186
OpenAlexW4210330762

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.