Evidence map›Paper›PMID 35173691›Full record

ReviewFrontiers in microbiology2021

Evasion of Host Antiviral Innate Immunity by Paramyxovirus Accessory Proteins.

Chongyang Wang, Ting Wang, Liuyuan Duan, Hui Chen, Ruochen Hu, Xiangwei Wang, Yanqing Jia, Zhili Chu, Haijin Liu, Xinglong Wang and 5 more

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 35 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Activation and Evasion of the FEAR Pathway by RNA Viruses.bioRxiv : the preprint server for biology · 2025
    Article
  10. Review
  11. Review
  12. Review
  13. CRISPR-Cas System: A New Dawn to Combat Antibiotic Resistance.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2024
    Review
  14. Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Chongyang WangCollege of Veterinary Medicine, Northwest A&F University, Xianyang, China.
Ting WangCollege of Veterinary Medicine, Northwest A&F University, Xianyang, China.
Liuyuan DuanCollege of Veterinary Medicine, Northwest A&F University, Xianyang, China.
Hui ChenCollege of Veterinary Medicine, Northwest A&F University, Xianyang, China.
Ruochen HuCollege of Veterinary Medicine, Northwest A&F University, Xianyang, China.
Xiangwei WangCollege of Veterinary Medicine, Northwest A&F University, Xianyang, China.
Yanqing JiaCollege of Veterinary Medicine, Northwest A&F University, Xianyang, China.
Zhili ChuCollege of Veterinary Medicine, Northwest A&F University, Xianyang, China.
Haijin LiuCollege of Veterinary Medicine, Northwest A&F University, Xianyang, China.
Xinglong WangCollege of Veterinary Medicine, Northwest A&F University, Xianyang, China.
Shuxia ZhangCollege of Veterinary Medicine, Northwest A&F University, Xianyang, China.
Sa XiaoCollege of Veterinary Medicine, Northwest A&F University, Xianyang, China.
Juan WangCollege of Veterinary Medicine, Northwest A&F University, Xianyang, China.
Ruyi DangCollege of Veterinary Medicine, Northwest A&F University, Xianyang, China.
Zengqi YangCollege of Veterinary Medicine, Northwest A&F University, Xianyang, China.
Northwest A&F University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For efficient replication, viruses have developed multiple strategies to evade host antiviral innate immunity. Paramyxoviruses are a large family of enveloped RNA viruses that comprises diverse human and animal pathogens which jeopardize global public health and the economy. The accessory proteins expressed from the P gene by RNA editing or overlapping open reading frames (ORFs) are major viral immune evasion factors antagonizing type I interferon (IFN-I) production and other antiviral innate immune responses. However, the antagonistic mechanisms against antiviral innate immunity by accessory proteins differ among viruses. Here, we summarize the current understandings of immune evasion mechanisms by paramyxovirus accessory proteins, specifically how accessory proteins directly or indirectly target the adaptors in the antiviral innate immune signaling pathway to facilitate virus replication. Additionally, some cellular responses, which are also involved in viral replication, will be briefly summarized.

Indexed as

accessory proteinsantiviral innate immunityIFNimmune evasionparamyxoviruses

Identifiers

PMID35173691
PMCPMC8841848
OpenAlexW4210645564

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.