Evidence map›Paper›PMID 35173668›Full record

ReviewFrontiers in neurology2021

Fluid and Tissue Biomarkers of Lewy Body Dementia: Report of an LBDA Symposium.

Gregory D Scott, Moriah R Arnold, Thomas G Beach, Christopher H Gibbons, Anumantha G Kanthasamy, Russell M Lebovitz, Afina W Lemstra, Leslie M Shaw, Charlotte E Teunissen, Henrik Zetterberg and 35 more

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Where do PDD and DLB SYNdromes fit in neuronal alpha-SYNuclein biological frameworks?Journal of neural transmission (Vienna, Austria : 1996) · 2026
    Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Fluid and Biopsy Based Biomarkers in Parkinson's Disease.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2023
    Review
  15. Review
  16. Race and Ethnicity in Lewy Body Dementia: A Narrative Review.Journal of Alzheimer's disease : JAD · 2023
    Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

45 authors at 20 institutions in 4 countries.

Gregory D ScottDepartment of Pathology, Oregon Health and Science University, Portland, OR, United States.
Moriah R ArnoldGraduate Program in Biomedical Sciences, School of Medicine M.D./Ph.D. Program, Oregon Health and Science University, Portland, OR, United States.
Thomas G BeachCivin Laboratory for Neuropathology and Brain and Body Donation Program, Banner Sun Health Research Institute, Sun City, AZ, United States.
Christopher H GibbonsDepartment of Neurology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, United States.
Anumantha G KanthasamyDepartment of Physiology and Pharmacology, Center for Brain Sciences and Neurodegenerative Diseases, University of Georgia, Athens, GA, United States.
Russell M LebovitzAmprion Inc., San Francisco, CA, United States.
Afina W LemstraDepartment of Neurology, Amsterdam University Medical Center (UMC), Alzheimer Center Amsterdam, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Leslie M ShawDepartment of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
Charlotte E TeunissenNeurochemistry Laboratory, Department of Clinical Chemistry, Amsterdam Neuroscience, Amsterdam University Medical Center (UMC), Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Henrik ZetterbergDepartment of Psychiatry and Neurochemistry, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.
Angela S TaylorLewy Body Dementia Association, Lilburn, GA, United States.
Todd C GrahamLewy Body Dementia Association, Lilburn, GA, United States.
Bradley F BoeveDepartment of Neurology and Center for Sleep Medicine, Mayo Clinic, Rochester, MN, United States.
Stephen N GompertsDepartment of Neurology, Massachusetts General Hospital, Boston, MA, United States.
Neill R Graff-RadfordDepartment of Neurology, Mayo Clinic, Jacksonville, FL, United States.
Charbel MoussaDepartment of Neurology, Georgetown University Medical Center, Washington DC, CA, United States.
Kathleen L PostonDepartment of Neurology and Neurological Sciences, Stanford University, Stanford, CA, United States.
Liana S RosenthalDepartment of Neurology, Johns Hopkins School of Medicine, Baltimore, MD, United States.
Marwan N SabbaghDepartment of Neurology, Barrow Neurological Institute, Phoenix, AZ, United States.
Ryan R WalshBarrow Neurological Institute and Muhammed Ali Parkinson Center, Phoenix, AZ, United States.
Miriam T WeberDepartment of Neurology, University of Rochester, Rochester, NY, United States.
Melissa J ArmstrongDepartment of Neurology, University of Florida College of Medicine, Gainesville, FL, United States.
Jee A BangDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Andrea C BozokiDepartment of Neurology, University of North Carolina, Chapel Hill, NC, United States.
Kimiko Domoto-ReillyDepartment of Neurology, University of Washington, Seattle, WA, United States.
John E DudaParkinson's Disease Research, Education and Clinical Center, Michael J. Crescenz VA Medical Center, Philadelphia, PA, United States.
Jori E FleisherDepartment of Neurological Sciences, Rush Medical College, Chicago, IL, United States.
Douglas R GalaskoDepartment of Neurosciences, University of California, San Diego, San Diego, CA, United States.
James E GalvinDepartment of Neurology, Comprehensive Center for Brain Health, University of Miami Miller School of Medicine, Miami, FL, United States.
Jennifer G GoldmanShirley Ryan Abilitylab and Department of Physical Medicine and Rehabilitation and Neurology, Parkinson's Disease and Movement Disorders, Northwestern University Feinberg School of Medicine, Chicago, IL, United States.
Samantha K HoldenDepartment of Neurology, University of Colorado School of Medicine, Aurora, CO, United States.
Lawrence S HonigColumbia University Irving Medical Center, New York, NY, United States.
Daniel E HuddlestonDepartment of Neurology, Emory University School of Medicine, Atlanta, GA, United States.
James B LeverenzLou Ruvo Center for Brain Health, Cleveland Clinic, Cleveland, OH, United States.
Irene LitvanDepartment of Neurosciences, University of California, San Diego, San Diego, CA, United States.
Carol A ManningDepartment of Neurology, University of Virginia, Charlottesville, VA, United States.
Karen S MarderColumbia University Irving Medical Center, New York, NY, United States.
Alexander Y PantelyatDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Victoria S PelakDepartments of Neurology and Ophthalmology, University of Colorado School of Medicine, Aurora, CO, United States.
Douglas W ScharreDepartment of Neurology, Ohio State University Wexner Medical Center, Columbus, OH, United States.
Sharon J ShaDepartment of Neurology and Neurological Sciences, Stanford University, Stanford, CA, United States.
Holly A ShillDepartment of Neurology, Barrow Neurological Institute, Phoenix, AZ, United States.
Zoltan MariLou Ruvo Center for Brain Health, Cleveland Clinic Lerner College of Medicine, Las Vegas, NV, United States.
Joseph F QuinnDepartment of Neurology, Oregon Health and Science University, Portland, OR, United States.
David J IrwinDepartment of Neurology, University of Pennsylvania Health System, Philadelphia, PA, United States.
Barrow Neurological Institute · USColumbia University Irving Medical Center · USJohns Hopkins University · USOregon Health & Science University · USStanford University · USUniversity of California, San Diego · USUniversity of Colorado Denver · USAmprion (United States) · USAmsterdam Neuroscience · NLBanner Sun Health Research Institute · USBeth Israel Deaconess Medical Center · USCleveland Clinic · USEmory University · USGeorgetown University · USJohns Hopkins Medicine · USLou Ruvo Brain Institute · USMassachusetts General Hospital · USMayo Clinic · USMayo Clinic in Florida · USPhiladelphia VA Medical Center · US

Funding

Research Education ComponentP30AG062421 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI STEVEN E ARNOLD · 2019 to 2026
$36.5M
Translational and Therapeutics CoreP30AG072959 · NIA · CLEVELAND CLINIC LERNER COM-CWRU · PI Mark J Lowe · 2021 to 2026
$23.9M
Project IV "Tackling Heterogeneity of Cognitive Trajectory in LBD"U19AG062418 · NIA · UNIVERSITY OF PENNSYLVANIA · PI WEINTRAUB, DANIEL · 2019 to 2023
$18.1M
Dementia with Lewy Bodies Consortium - Supplement for ASL sequenceU01NS100610 · NINDS · SEATTLE INST FOR BIOMEDICAL/CLINICAL RES · PI DOUGLAS R GALASKO, JAMES Bruce LEVERENZ · 2016 to 2026
$15.6M
Multicultural Community Dementia ScreeningR01AG071514 · NIA · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI GALVIN, JAMES E · 2021 to 2025
$13.8M
MRI Signatures of Neuromelanin and Iron Pathology in ParkinsonismK23NS105944 · NINDS · EMORY UNIVERSITY · PI HUDDLESTON, DANIEL · 2018 to 2022
$963k
BLRD VA IK2 BX005760NIA NIH HHS P30 AG062421NIA NIH HHS P30 AG072959NIA NIH HHS R01 AG071514NIA NIH HHS U19 AG062418NINDS NIH HHS K23 NS105944NINDS NIH HHS U01 NS100610
6 · The paper itself

Abstract

The Lewy Body Dementia Association (LBDA) held a virtual event, the LBDA Biofluid/Tissue Biomarker Symposium, on January 25, 2021, to present advances in biomarkers for Lewy body dementia (LBD), which includes dementia with Lewy bodies (DLBs) and Parkinson's disease dementia (PDD). The meeting featured eight internationally known scientists from Europe and the United States and attracted over 200 scientists and physicians from academic centers, the National Institutes of Health, and the pharmaceutical industry. Methods for confirming and quantifying the presence of Lewy body and Alzheimer's pathology and novel biomarkers were discussed.

Indexed as

alpha-synucleinamyloidcerebrospinal fluidLBDA biomarker symposiumLewy body dementiaseeded aggregation assaysskin biopsytau

Identifiers

PMID35173668
PMCPMC8841880
OpenAlexW4220654530

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.