Evidence map›Paper›PMID 35173552›Full record

ArticleInternational journal of biological sciences2022

CXCR4-dependent macrophage-to-fibroblast signaling contributes to cardiac diastolic dysfunction in heart failure with preserved ejection fraction.

Ning Zhang, Qunchao Ma, Yayu You, Xiangyang Xia, Cuiping Xie, Yuxue Huang, Zhuo Wang, Feiming Ye, Zhaosheng Yu, Xiaojie Xie

Open access · goldAbstract read
In one paragraph

Article in International journal of biological sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 2 pooled it
10.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 2 syntheses or guidelines pooled it, 59 citations in OpenAlex.

  1. Immunology of heart failure with preserved ejection fraction.Expert review of clinical immunology · 2025
    Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Multi-omics reveals a novel Cxcr4Clinical and translational medicine · 2026
    Article
  7. Review
  8. RelJournal of translational medicine · 2026
    Article
  9. The value ofHypertension research : official journal of the Japanese Society of Hypertension · 2026
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Review
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Ning ZhangDepartment of Cardiology, Cardiovascular Key Laboratory of Zhejiang Province, Second Affiliated Hospital, Zhejiang University College of Medicine, 88 Jiefang Rd, Hangzhou, Zhejiang Province, 310009, PR China.
Qunchao MaDepartment of Cardiology, Cardiovascular Key Laboratory of Zhejiang Province, Second Affiliated Hospital, Zhejiang University College of Medicine, 88 Jiefang Rd, Hangzhou, Zhejiang Province, 310009, PR China.
Yayu YouDepartment of Cardiology, Cardiovascular Key Laboratory of Zhejiang Province, Second Affiliated Hospital, Zhejiang University College of Medicine, 88 Jiefang Rd, Hangzhou, Zhejiang Province, 310009, PR China.
Xiangyang XiaDepartment of Cardiology, Cardiovascular Key Laboratory of Zhejiang Province, Second Affiliated Hospital, Zhejiang University College of Medicine, 88 Jiefang Rd, Hangzhou, Zhejiang Province, 310009, PR China.
Cuiping XieDepartment of Cardiology, Cardiovascular Key Laboratory of Zhejiang Province, Second Affiliated Hospital, Zhejiang University College of Medicine, 88 Jiefang Rd, Hangzhou, Zhejiang Province, 310009, PR China.
Yuxue HuangDepartment of Cardiology, Cardiovascular Key Laboratory of Zhejiang Province, Second Affiliated Hospital, Zhejiang University College of Medicine, 88 Jiefang Rd, Hangzhou, Zhejiang Province, 310009, PR China.
Zhuo WangDepartment of Cardiology, Cardiovascular Key Laboratory of Zhejiang Province, Second Affiliated Hospital, Zhejiang University College of Medicine, 88 Jiefang Rd, Hangzhou, Zhejiang Province, 310009, PR China.
Feiming YeDepartment of Cardiology, Cardiovascular Key Laboratory of Zhejiang Province, Second Affiliated Hospital, Zhejiang University College of Medicine, 88 Jiefang Rd, Hangzhou, Zhejiang Province, 310009, PR China.
Zhaosheng YuState Key Laboratory of Fluid Power and Mechatronic Systems, Department of Mechanics, Zhejiang University, Hangzhou 310027, China.
Xiaojie XieDepartment of Cardiology, Cardiovascular Key Laboratory of Zhejiang Province, Second Affiliated Hospital, Zhejiang University College of Medicine, 88 Jiefang Rd, Hangzhou, Zhejiang Province, 310009, PR China.
Second Affiliated Hospital of Zhejiang University · CNZhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CardiomyopathiesHeart FailureHypertensionAnimalsCytokinesFibroblastsMacrophagesMiceReceptors, CXCR4Stroke VolumeVentricular Function, LeftVentricular RemodelingCXCR4 protein, mouseCytokinesReceptors, CXCR4CXCR4fibrosisHFpEFinflammationmacrophages

Identifiers

PMID35173552
PMCPMC8771855
OpenAlexW4205473419

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.