Evidence map›Paper›PMID 35173500›Full record

ArticleNature and science of sleep2022

Daytime Sleep Behaviors and Cognitive Performance in Middle- to Older-Aged Adults Living with and without HIV Infection.

Peng Li, Lei Gao, Chenlu Gao, Robert A Parker, Ingrid T Katz, Monty A Montano, Kun Hu

Abstract read
In one paragraph

Article in Nature and science of sleep, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Peng LiMedical Biodynamics Program, Division of Sleep and Circadian Disorders, Departments of Medicine and Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-4684-4909
Lei GaoMedical Biodynamics Program, Division of Sleep and Circadian Disorders, Departments of Medicine and Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.ORCID 0000-0003-1476-1460
Chenlu GaoMedical Biodynamics Program, Division of Sleep and Circadian Disorders, Departments of Medicine and Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Robert A ParkerBiostatistics Center, Massachusetts General Hospital, Boston, MA, USA.
Ingrid T KatzHarvard Medical School, Boston, MA, USA.
Monty A MontanoHarvard Medical School, Boston, MA, USA.
Kun HuMedical Biodynamics Program, Division of Sleep and Circadian Disorders, Departments of Medicine and Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.ORCID 0000-0003-0350-3132

Funding

The impact of HIV viral diversity and cellular immunity on HIV pathogenesisP30AI060354 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI RAJESH T GANDHI · 2004 to 2026
$94.4M
TUFTS--FIELDINGP30AG031679 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI SHALENDER BHASIN · 2008 to 2026
$23.9M
HIV and Aging Research Consortium (HARC)R33AG067069 · NIA · UNIVERSITY OF WASHINGTON · PI STEVEN N. AUSTAD, Heidi M. Crane · 2020 to 2026
$4.8M
Integrative Motor Activity Biomarker for the Risk of Alzheimer's RiskRF1AG064312 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI HU, KUN · 2019 to 2019
$3.6M
Fractal motor activity regulation and the risk for Alzheimers disease in middle-to-old aged adultsRF1AG059867 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI HU, KUN · 2018 to 2018
$2.7M
Circadian Multiscale Activity Regulation and the Risk for Delirium in Elderly Hospitalized PatientsR03AG067985 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI GAO, LEI · 2020 to 2021
$268k
NIAID NIH HHS P30 AI060354NIA NIH HHS P30 AG031679NIA NIH HHS R03 AG067985NIA NIH HHS R33 AG067069NIA NIH HHS RF1 AG059867NIA NIH HHS RF1 AG064312
6 · The paper itself

Abstract

purposeWe investigated whether daytime sleep behaviors (DSBs) such as frequent daytime sleepiness or napping are associated with worse cognitive performance, and whether HIV infection moderates this relationship.

methodsAmong 502,507 participants in the UK Biobank study, we identified 562 people living with HIV infection (PLWH;

resultsHaving poor DSB burden was associated with a 0.15 - standard deviation (SD) decrease in cognitive performance (

conclusionHIV infection significantly increased the adverse association between DSBs and cognitive performance. Further studies are needed to investigate the potential mechanisms that underlie this interaction effect and whether poor DSBs and worse cognitive performance are causally linked.

Indexed as

agingcognitiondaytime nappingdaytime sleepinessrisk factorssleep

Identifiers

PMID35173500
PMCPMC8843344

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.