ArticleInternational journal of general medicine2022
Relationship Between the Triglyceride Glucose Index and the Risk of First Stroke in Elderly Hypertensive Patients.
Article in International journal of general medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
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Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The impact of triglyceride-glucose index on ischemic stroke: a systematic review and meta-analysis.Cardiovascular diabetology · 2023Pooled it
- Association between triglyceride glucose index and risk of cerebrovascular disease: systematic review and meta-analysis.Cardiovascular diabetology · 2022Pooled it
- Interplay between triglyceride-glucose index and cardiovascular events in hypertensive patients with controlled blood pressure (SBP<140 mmHg): insights from the SPRINT trial.Frontiers in endocrinology · 2025Trial
- Association of the Triglyceride-Glucose Index with Ambulatory Blood Pressure Categories and Circadian Blood Pressure Phenotypes in Untreated Adults: A Single-Centre, ABPM-Based Retrospective Cross-Sectional Study.Diagnostics (Basel, Switzerland) · 2026Article
- Article
- Outcomes of endovascular thrombectomy in acute ischemic stroke patients with insulin resistance.Journal of neurointerventional surgery · 2026Article
- Triglyceride-glucose index threshold for cardiovascular mortality in hypertensive individuals - URRAH project.American journal of preventive cardiology · 2025Article
- Prognostic value of triglyceride-glucose index on predicting major adverse cardiovascular events in hypertensive patients: a systematic review and meta-analysis.American journal of preventive cardiology · 2025Article
- The predictive significance of the triglyceride-glucose index in forecasting adverse cardiovascular events among type 2 diabetes mellitus patients with co-existing hyperuricemia: a retrospective cohort study.Cardiovascular diabetology · 2025Article
- Triglyceride-glucose index predicts adverse cardiovascular events in patients with H-type hypertension combined with coronary heart disease: a retrospective cohort study.Cardiovascular diabetology · 2025Article
- Association of Lipid and Blood Glucose Profiles with MASLD Among Young Adults.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025Article
- Exploring the prognostic impact of triglyceride-glucose index in critically ill patients with first-ever stroke: insights from traditional methods and machine learning-based mortality prediction.Cardiovascular diabetology · 2024Article
- Article
- Predictive value of the triglyceride-glucose index for short- and long-term all-cause mortality in patients with critical coronary artery disease: a cohort study from the MIMIC-IV database.Lipids in health and disease · 2024Article
- The nonlinear relationship between triglyceride glucose-waist circumference and stroke risk in middle-aged and elderly people: a nationwide prospective cohort study of the CHARLS.Lipids in health and disease · 2024Observational
- Associations of triglyceride-glucose (TyG) index with chest pain incidence and mortality among the U.S. population.Cardiovascular diabetology · 2024Article
- Relationship between TyG index and the degree of coronary artery lesions in patients with H-type hypertension.Cardiovascular diabetology · 2024Article
- Association between the Triglyceride-Glucose Index and Non-Alcoholic Fatty Liver Disease in patients with Atrial Fibrillation.European journal of medical research · 2023Article
- Prevalence estimates of the insulin resistance and associated prevalence of heart failure among United Status adults.BMC cardiovascular disorders · 2023Article
- Study on insulin resistance and ischemic cerebrovascular disease: A bibliometric analysisFrontiers in public health · 2023Review
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Authors and funding
9 authors.
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Abstract
backgroundSeveral recent studies have shown the relationship between the triglyceride glucose (TyG) index and the risk of stroke in the general population and in a few patient cohorts; however, the role of the TyG index on stroke risk in elderly hypertensive patients has not been determined. Thus, we aimed to investigate the association of the TyG index with first stroke and first ischemic stroke in elderly individuals with hypertension.
methodsWe included 8487 elderly subjects with hypertension from the China H-type Hypertension Registry Study for the current analysis. The TyG index was calculated as ln (fasting triglyceride [mg/dL] × fasting glucose [mg/dL]/2). Outcomes were the first stroke and first ischemic stroke.
resultsDuring a median follow-up of 1.72 years, the first stroke was diagnosed in 82 patients (0.97%), and the first ischemic stroke was diagnosed in 48 patients (0.57%). Multivariable Cox proportional hazards models revealed that the TyG index was positively associated with the risk of first stroke (per 1-unit increment; HR: 1.72; 95% CI: 1.07, 2.76) and first ischemic stroke (HR: 2.31; 95% CI: 1.32, 4.05). When the TyG index was assessed as quartiles, significantly higher risks of first stroke (HR: 1.90; 95% CI: 1.04, 3.45) and first ischemic stroke (HR: 2.45; 95% CI: 1.16, 5.20) were found in participants in quartile 4 compared with those in quartiles 1-3.
conclusionThe TyG index is potentially useful in the early identification of elderly hypertensive patients at high risk of experiencing a first stroke.
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