Evidence map›Paper›PMID 35173462›Full record

ArticleInternational journal of general medicine2022

Association of Smoking with the Blood Concentration of 25-Hydroxy Vitamin D and Testosterone at High and Low Altitudes.

Gaffar Sarwar Zaman, Safar Abadi Saeed Al-Saleem Alshahrani, Nasrin Banu Laskar, Ibrahim Hadadi, Magbool Alelyani, Mohamed Adam, Mohammed Babiker, Mustafa Jafar Musa, Pranab Barua, Mohammed Elimam Ahamed Mohammed

Open access · goldAbstract read
In one paragraph

Article in International journal of general medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Gaffar Sarwar ZamanDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Khalid University, Abha, Saudi Arabia.ORCID 0000-0002-8740-3990
Safar Abadi Saeed Al-Saleem AlshahraniFamily & Community Department, College of Medicine, King Khalid University, Abha, Saudi Arabia.
Nasrin Banu LaskarDepartment of Community Medicine, Sikkim Manipal Institute of Medical Sciences, Sikkim, India.
Ibrahim HadadiDepartment of Radiological Sciences, College of Applied Medical Sciences, King Khalid University, Abha, Saudi Arabia.
Magbool AlelyaniDepartment of Radiological Sciences, College of Applied Medical Sciences, King Khalid University, Abha, Saudi Arabia.ORCID 0000-0002-6597-5090
Mohamed AdamDepartment of Radiological Sciences, College of Applied Medical Sciences, King Khalid University, Abha, Saudi Arabia.ORCID 0000-0002-7818-6744
Mohammed BabikerDepartment of Clinical Biochemistry, College of Medicine, King Khalid University, Abha, Saudi Arabia.
Mustafa Jafar MusaDepartment of Radiology, College of Applied Medical Sciences, Jeddah University, Jeddah, Saudi Arabia.
Pranab BaruaDepartment of Statistics, J.B. College, Jorhat, Assam, India.
Mohammed Elimam Ahamed MohammedDepartment of Chemistry, Faculty of Science, King Khalid University, Abha, Saudi Arabia.
King Khalid University · SAInstitute of Medical Sciences · INUniversity of Jeddah · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis research examined the association of cigarette smoking and altitude with the blood levels of 25-hydroxy vitamin D, testosterone and carotid artery thickness. PATIENTS AND

methodsThis comparative cross-sectional study involved 37 non-smokers and 24 smokers from a high-altitude area (≥2245 m above sea level) and 40 smokers and 40 non-smokers from a low-altitude area (39-283 m above sea level). The blood testosterone level was determined spectrophotometrically, and the 25-hydroxy vitamin D concentration was measured by ELISA. The IMT of the right and left carotid arteries was determined using ultrasound imaging.

resultsSmoking notably elevated the thickness of the intima media of the right and left carotid arteries at both high and low altitudes (

conclusionThese contrasting results suggest that future studies should focus on finding out if other biochemical parameters show any significant differences in smokers or/and non-smokers when they are tested at elevated height and sea-level. This indicates that dose modifications of medicines (related to alterations in vitamin D and testosterone levels) should be kept in mind while treating smokers and non-smokers at elevated height above sea level.

Indexed as

agingaltitudebody mass indexintima media thicknesssmoking

Identifiers

PMID35173462
PMCPMC8835976
OpenAlexW4210928229

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.