ArticleJournal of inflammation research2022
Gender-Specific Impact of Metabolic Obesity Phenotypes on the Risk of Hashimoto's Thyroiditis: A Retrospective Data Analysis Using a Health Check-Up Database.
Article in Journal of inflammation research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 18 citations in OpenAlex.
- Identification of potential biomarkers and therapeutic targets for liver cirrhosis based on Mendelian randomization and machine learning.Biochemistry and biophysics reports · 2026Article
- Hypoxia-Inducible Factor 1-α in Autoimmune Diseases-Insights from the Paradigm of Hashimoto's Thyroiditis: A Narrative Review.Medical sciences (Basel, Switzerland) · 2026Review
- Association ofInternational journal of molecular sciences · 2025Article
- EndoCompass Project: Research Roadmap for Thyroid Endocrinology.Hormone research in paediatrics · 2025Review
- Relationship of different metabolic obesity phenotypes with reflux esophagitis: a propensity score matching analysis.BMC endocrine disorders · 2024Article
- Association between systemic immune-inflammation index and sarcopenic obesity in middle-aged and elderly Chinese adults: a cross-sectional study and mediation analysis.Lipids in health and disease · 2024Article
- Analysis of risk factors for autoimmune thyroid disease based on blood indicators and urinary iodine concentrations.Frontiers in endocrinology · 2024Article
- Identification of atrial fibrillation-related genes through transcriptome data analysis and Mendelian randomization.Frontiers in cardiovascular medicine · 2024Article
- Association Between Different Metabolic Obesity Phenotypes and Erosive Esophagitis: A Retrospective Study.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024Article
- Association between weight-adjusted waist index and Hashimoto's thyroiditis: insights from NHANES 2007-2012.Frontiers in nutrition · 2024Article
- Causal association between body mass index and autoimmune thyroiditis: evidence from Mendelian randomization.European journal of medical research · 2023Article
- Gender difference in association between low muscle mass and risk of non-alcoholic fatty liver disease among Chinese adults with visceral obesity.Frontiers in nutrition · 2023Article
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Authors and funding
6 authors at 1 institution in 1 country.
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Abstract
backgroundHashimoto's thyroiditis (HT) is recognized as the most common autoimmune thyroid disease, often accompanied by the diffuse enlargement of thyroid with abundant blood flow and elevated level of thyroid autoantibodies. As obesity had a positive association with the risk of HT. Thus, this retrospective study was established to further explore the gender relationship between metabolic obesity phenotypes and the risk of Hashimoto's thyroiditis (HT). MATERIALS AND
methodsData for 3697 subjects aged ≥18 years were randomly collected from a Health check-up database from April to December 2019. Obesity was defined by general obesity (GO; body mass index [BMI] ≥28 kg/m
resultsThe incidence of HT was 23.5% and significantly higher among females than males with different metabolic phenotypes (26.2% vs 20.5%,
conclusionGO+AO was associated with an increased risk of HT, identifying higher BMI/WC as a significant risk factor for HT. Males with unhealthy metabolic state or obesity and metabolically unhealthy females with obesity are high-risk group for HT. Additionally, only AO and GO+AO conferred increased risk of HT for individuals with metabolic abnormalities.
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