Evidence map›Paper›PMID 35173399›Full record

ArticleJournal of current glaucoma practice

Late-onset Endophthalmitis after XEN45

Raquel Burggraaf-Sánchez de Las Matas, Laura Such-Irusta, Enrique A Alfonso-Muñoz, Héctor Mascarós-Mena, Aitor Lanzagorta-Aresti, Jorge Mataix-Boronat, Carolina Font-Julià

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Journal of current glaucoma practice. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Endophthalmitis Associated With XEN Stent Implantation.American journal of ophthalmology · 2023
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Raquel Burggraaf-Sánchez de Las MatasDepartment of Glaucoma-Ophthalmology, University Hospital of Castellón, Castellón, Spain.
Laura Such-IrustaDepartment of Ophthalmology, Hospital of Sagunto, Sagunto, Valencia, Spain.
Enrique A Alfonso-MuñozDepartment of Vitreoretinal Diseases, FISABIO-Medical Ophthalmology (FOM), Valencia, Spain.
Héctor Mascarós-MenaDepartment of Ophthalmology, Hospital of Sagunto, Sagunto, Valencia, Spain.
Aitor Lanzagorta-ArestiDepartment of Glaucoma, FISABIO-Medical Ophthtalmology (FOM), Valencia, Spain.
Jorge Mataix-BoronatDepartment of Vitreoretinal Diseases, FISABIO-Medical Ophthalmology (FOM), Valencia, Spain.
Carolina Font-JuliàDepartment of Ophthalmology, Hospital of Sagunto, Sagunto, Valencia, Spain.
Hospital de Sagunto · ESFundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

AIM AND

objectiveTo report the incidence of late-onset endophthalmitis following XEN45

backgroundLong-term safety profile and efficacy in relation to the so-called microinvasive glaucoma surgery (MIGS) techniques are still under evaluation. The XEN45 CASES DESCRIPTION: From our chart of 293 eyes operated on between November 2016 and November 2019, five (1.7%) patients developed endophthalmitis, which took place in the months 3, 4, 5, 11, and 14 after surgery, respectively. Sixty percent had undergone previous needling procedures. All of them showed a previous flat bleb and developed perforation of the conjunctiva caused by the distal portion of the tube. One patient was early eviscerated due to a fateful course. Treatment consisted of intravitreal, oral, and topical antibiotics, as well as topical corticosteroids. Eighty percent underwent device withdrawal, conjunctival gap suturing, anterior chamber washout, aqueous humor (AH) tab extraction (one positive for

conclusionThe XEN45 CLINICAL SIGNIFICANCE: This series shows a higher rate of endophthalmitis (1.7%) compared with previous studies with a significant sample size (0.4-1.4%). HOW TO CITE THIS ARTICLE: Burggraaf-Sánchez de las Matas R, Such-Irusta L, Alfonso-Muñoz EA,

Indexed as

EndophthalmitisMicroinvasive glaucoma surgeryMinimally penetrating glaucoma surgeryNeedlingRetrospective case seriesSafety-profileXEN45® gel stent

Identifiers

PMID35173399
PMCPMC8807934
OpenAlexW4210635674

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.