Evidence map›Paper›PMID 35173384›Full record

ArticleBioinformation2021

Molecular docking analysis of COX-2 with compounds from Piper longum.

Dhirendra Tripathi, Sravanthi Koora, K Satyanarayana, S Saleem Basha, Selvaraj Jayaraman

Abstract read
In one paragraph

Article in Bioinformation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Rapid Screening of Chemical Components inInternational journal of molecular sciences · 2024
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dhirendra TripathiDepartment of Otorhinolaryngology, Government Medical College, Shivpuri, Shivpuri - 473638.
Sravanthi KooraDepartment of Pharmacology, Government Medical College Siddipet 502103, Siddipet, Telangana.
K SatyanarayanaDepartment of Biochemistry, Government Medical College Siddipet,Siddipet 502103, Telangana India.
S Saleem BashaDepartment of Medical Biochemistry, School of Medicine, Haramaya university, Harar Campus,Ethiopia.
Selvaraj JayaramanDepartment of Biochemistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences,Chennai-600 077, Indi.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Piper longum (Indian long pepper) is known for its use as an anti inflammatory agent in Indian Ayurvedic System of medicine. Therefore, it is of interest to document the molecular docking analysis of compounds from Piper longum with COX-2 using the Autodock Vina PyRx tool. Molecular docking results show that asarinine, sesamine, fargesin, and piperlonguminine have optimal binding energy of 10, 10, -9.5 and 9.4 Kcal/mol, respectively for further consideration.

Indexed as

Anti-inflammatory compundsCOX-2molecular dockingPiper longum

Identifiers

PMID35173384
PMCPMC8819790

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.