Evidence map›Paper›PMID 35173309›Full record

ArticleOncogene2022

LINC01021 maintains tumorigenicity by enhancing N6-methyladenosine reader IMP2 dependent stabilization of MSX1 and JARID2: implication in colorectal cancer.

Huizhe Wu, Xiangyu Ding, Xiaoyun Hu, Qing Zhao, Qiuchen Chen, Tong Sun, Yalun Li, Hao Guo, Meng Li, Ziming Gao and 4 more

Abstract read
PubMed Publisher
In one paragraph

Article in Oncogene, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. IMPlications of IMP2 in RNA Biology and Disease.International journal of molecular sciences · 2025
    Review
  6. Review
  7. Review
  8. Review
  9. The mMolecular cancer · 2024
    Article
  10. IGF2BPs as novel mGenes & diseases · 2024
    Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. Review
  16. Review
  17. New insights on the interplays between mFrontiers in cell and developmental biology · 2023
    Review
  18. JMJD family proteins in cancer and inflammation.Signal transduction and targeted therapy · 2022
    Review
  19. The role of Insulin-like growth factor 2 mRNA-binding proteins (IGF2BPs) as mInternational journal of biological sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Huizhe Wu *Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, 110122, PR China.ORCID http://orcid.org/0000-0001-7964-1342
Xiangyu Ding *Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, 110122, PR China.
Xiaoyun Hu *Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, 110122, PR China.
Qing ZhaoDepartment of Pharmacology, School of Pharmacy, China Medical University, Shenyang, 110122, PR China.
Qiuchen ChenDepartment of Pharmacology, School of Pharmacy, China Medical University, Shenyang, 110122, PR China.
Tong SunDepartment of Pharmacology, School of Pharmacy, China Medical University, Shenyang, 110122, PR China.
Yalun LiDepartment of Anorectal Surgery, First Affiliated Hospital of China Medical University, Shenyang, 110001, PR China.
Hao GuoDepartment of Pharmacology, School of Pharmacy, China Medical University, Shenyang, 110122, PR China.
Meng LiDepartment of Pharmacology, School of Pharmacy, China Medical University, Shenyang, 110122, PR China.
Ziming GaoDepartment of Surgical Oncology and General Surgery, Key Laboratory of Precision Diagnosis and Treatment of Gastrointestinal Tumors, Ministry of Education, First Affiliated Hospital of China Medical University, Shenyang, 110001, PR China.
Weifan YaoDepartment of Pharmacology, School of Pharmacy, China Medical University, Shenyang, 110122, PR China.ORCID http://orcid.org/0000-0001-8878-2649
Lin ZhaoDepartment of Pharmacology, School of Pharmacy, China Medical University, Shenyang, 110122, PR China.ORCID http://orcid.org/0000-0001-9264-6455
Kai LiDepartment of Surgical Oncology and General Surgery, Key Laboratory of Precision Diagnosis and Treatment of Gastrointestinal Tumors, Ministry of Education, First Affiliated Hospital of China Medical University, Shenyang, 110001, PR China. cmu_likai@163.com.
Minjie WeiDepartment of Pharmacology, School of Pharmacy, China Medical University, Shenyang, 110122, PR China. mjwei@cmu.edu.cn.ORCID http://orcid.org/0000-0003-4812-2931
Ministry of Education · KNChina Medical University · CNFirst Hospital of China Medical University · CNShenyang Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Insulin-like growth factor-2 mRNA-binding protein 2 (IGF2BP2, also known as IMP2), a novel class III N6-methyladenosine (m

Indexed as

Colorectal NeoplasmsRNA, Long NoncodingAdenosineCarcinogenesisCell Line, TumorCell ProliferationGene Expression Regulation, NeoplasticHumansMSX1 Transcription FactorPolycomb Repressive Complex 2RNA-Binding ProteinsAdenosineIGF2BP2 protein, humanJARID2 protein, humanMSX1 protein, humanMSX1 Transcription FactorN-methyladenosinePolycomb Repressive Complex 2RNA-Binding ProteinsRNA, Long Noncoding

Identifiers

PMID35173309
OpenAlexW4212840043

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.