Evidence map›Paper›PMID 35173302›Full record

ArticlePediatric research2022

Regulatory T-lymphocyte subsets in children with chronic immune thrombocytopenia after high-dose of dexamethasone.

Khalid Ibrahim Elsayh, Khaled Saad, Naglaa Samy Osman, Khaled Hashim Mahmoud, Faisal A Ahmad, Shaimaa M Khalaf, Noha G Sayed, Zeinab Albadry M Zahran, Aliaa M A Ghandour, Amira A Elhoufey and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Pediatric research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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  5. Association of TCRαβFrontiers in immunology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Khalid Ibrahim ElsayhDepartment of Pediatrics, Faculty of Medicine, Assiut University, Assiut, Egypt.
Khaled SaadDepartment of Pediatrics, Faculty of Medicine, Assiut University, Assiut, Egypt. khaled.ali@med.au.edu.eg.
Naglaa Samy OsmanDepartment of Pediatrics, Faculty of Medicine, Assiut University, Assiut, Egypt.
Khaled Hashim MahmoudDepartment of Pediatrics, Faculty of Medicine, Assiut University, Assiut, Egypt.
Faisal A AhmadDepartment of Pediatrics, Faculty of Medicine, Assiut University, Assiut, Egypt.
Shaimaa M KhalafDepartment of Pediatrics, Faculty of Medicine, Assiut University, Assiut, Egypt.
Noha G SayedDepartment of clinical pathology, Faculty of Medicine, Assiut University, Assiut, Egypt.
Zeinab Albadry M ZahranDepartment of clinical pathology, Faculty of Medicine, Assiut University, Assiut, Egypt.
Aliaa M A GhandourDepartment of Medical Microbiology and Immunology, Faculty of Medicine, Assiut University, Assiut, Egypt.
Amira A ElhoufeyDepartment of Community Health Nursing, Faculty of Nursing, Assiut University, Assiut, Egypt.
Tamer BedirDepartment of Medical Microbiology and Immunology, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Asmaa ZahranDepartment of Clinical Pathology, South Egypt Cancer Institute, Assiut University, Assiut, Egypt.
Assiut University · EGMansoura University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundImmune thrombocytopenia (ITP) is an acquired autoimmune disease. This study's objective was to estimate the variations in the population of CD4

methodsIn this study, we investigated the frequencies of T-lymphocyte subsets in 27 untreated children with chronic ITP.

resultsPrior to treatment, the percentages of CD4

conclusionsOur results suggest that Tregs are deficient in children with chronic ITP and that HD-DXM immunosuppressive therapy can restore the levels of these cells. IMPACT: CD4

Indexed as

Purpura, Thrombocytopenic, IdiopathicAutoimmunityChildDexamethasoneHumansT-Lymphocytes, RegulatoryT-Lymphocyte SubsetsDexamethasone

Identifiers

PMID35173302
PMCPMC9700518
OpenAlexW4212811758

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.